Immunology-Auto Inflammation-Auto Immunity-Infection
Our immune system plays a central role in defending against pathogens such as bacteria and viruses, but also in the development and termination of inflammatory processes in the body. Malfunctions of the immune system can lead to diseases, the causes of which are often genetic. Disorders in the immune system can be associated with an increased susceptibility to infections or particularly severe infections. However, defects in the immune system can also cause inadequate inflammation or fever without an infection being present. Such autoinflammatory clinical pictures are often based on rare genetic defects of the innate immune system. Excessive reactions of the immune system to foreign antigens from the environment or to the body's own antigens can lead to autoimmune diseases or allergies. Clinically, fever and inflammation, e.g. of the skin, joints or kidneys, are often the main symptoms. The diagnosis and treatment should be in the hands of specialists who not only have clinical experience, but who also dedicate themselves to researching the causes of the disease and therapies and therefore have important insights into the latest scientific findings, therapeutic options and developments.
The cluster includes the Clinic and Polyclinic for Pediatric and Adolescent Medicine, the Clinic and Polyclinic for Dermatology, the Nephrology Department of Medical Clinic and Polyclinic III, and the Department of Extracorporeal Procedures and Lipoprotein Apheresis of Medical Clinic and Polyclinic III.
In this cluster, our center works closely with the University Cystic Fibrosis Center (UMC) "Christiane Herzog". Further information can be found directly on the UMC website.
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As part of the Clinic and Polyclinic for Pediatric and Adolescent Medicine, the USE is a member of the European reference network RITA (Rare Immunodeficiency, Autoinflammatory and Autoimmune Disease Network). |