Benutzerspezifische Werkzeuge

Epigenetics

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Lab Members

Adler, RomyTechnician
Friedemann, MarkusProject Leader
Gutewort, KatharinaMedical student
Horn, FriederikeMedical student
Jandeck, CarstenLab manager
Prof. Dr. Menschikowski, MarioGroup leader
Thiem, DanaMedical student

Selected Publications

  • Friedemann, M, Gutewort, K, Thiem, D, Nacke, B, Jandeck, C, Lange, B S, Sukocheva, O, Suttorp, M and Menschikowski, M. Methylation of the Phospholipase A2 Receptor 1 Promoter Region in Childhood B Cell Acute Lymphoblastic Leukaemia. Sci Rep 10: 9058 (2020)

  • Sukocheva, O A, Furuya, H, Ng, M L, Friedemann, M, Menschikowski, M, Tarasov, V V, Chubarev, V N, Klochkov, S G, Neganova, M E, Mangoni, A A, Aliev, G and Bishayee, A. Sphingosine kinase and sphingosine-1-phosphate receptor signaling pathway in inflammatory gastrointestinal disease and cancers: A novel therapeutic target. Pharmacol Ther 207: 107464 (2020)

  • Sukocheva, O A, Lukina, E, Friedemann, M, Menschikowski, M, Hagelgans, A and Aliev, G. The crucial role of epigenetic regulation in breast cancer anti-estrogen resistance: Current findings and future perspectives. Semin Cancer Biol(2020)

  • Sukocheva, O, Menschikowski, M, Hagelgans, A, Yarla, N S, Siegert, G, Reddanna, P and Bishayee, A. Current insights into functions of phospholipase A2 receptor in normal and cancer cells: More questions than answers. Semin Cancer Biol 56: 116-127 (2019)

  • Friedemann, M, Nacke, B, Hagelgans, A, Jandeck, C, Bechmann, N, Ullrich, M, Belter, B, Neuber, C, Sukocheva, O, Pietzsch, J and Menschikowski, M. Diverse effects of phospholipase A2 receptor expression on LNCaP and PC-3 prostate cancer cell growth in vitro and in vivo. Oncotarget 9: 35983-35996 (2018)

  • Menschikowski, M, Jandeck, C, Friedemann, M, Nacke, B, Hantsche, S, Tiebel, O, Sukocheva, O and Hagelgans, A. Identification of rare levels of methylated tumor DNA fragments using an optimized bias based pre-amplification-digital droplet PCR (OBBPA-ddPCR). Oncotarget 9: 36137-36150 (2018)

  • Menschikowski, M, Jandeck, C, Friedemann, M, Richter, S, Thiem, D, Lange, B S and Suttorp, M. Identification and Quantification of Heterogeneously-methylated DNA Fragments Using Epiallele-sensitive Droplet Digital Polymerase Chain Reaction (EAST-ddPCR). Cancer Genomics Proteomics 15: 299-312 (2018)

  • Hagelgans, A, Jandeck, C, Friedemann, M, Donchin, A, Richter, S and Menschikowski, M. Identification of CpG Sites of SERPINA5 Promoter with Opposite Methylation Patterns in Benign and Malignant Prostate Cells. Anticancer Res 37: 6609-6618 (2017)

Sukocheva, O, Menschikowski, M, Hagelgans, A, Yarla, N S, Siegert, G, Reddanna, P and Bishayee, A. Current insights into functions of phospholipase A2 receptor in normal and cancer cells: More questions than answers. Semin Cancer Biol56: 116-127 (2019)

  • Friedemann, M, Nacke, B, Hagelgans, A, Jandeck, C, Bechmann, N, Ullrich, M, Belter, B, Neuber, C, Sukocheva, O, Pietzsch, J and Menschikowski, M. Diverse effects of phospholipase A2 receptor expression on LNCaP and PC-3 prostate cancer cell growth in vitro and in vivo. Oncotarget9: 35983-35996 (2018)
  • Menschikowski, M, Jandeck, C, Friedemann, M, Nacke, B, Hantsche, S, Tiebel, O, Sukocheva, O and Hagelgans, A. Identification of rare levels of methylated tumor DNA fragments using an optimized bias based pre-amplification-digital droplet PCR (OBBPA-ddPCR). Oncotarget9: 36137-36150 (2018)
  • Menschikowski, M, Jandeck, C, Friedemann, M, Richter, S, Thiem, D, Lange, B S and Suttorp, M. Identification and Quantification of Heterogeneously-methylated DNA Fragments Using Epiallele-sensitive Droplet Digital Polymerase Chain Reaction (EAST-ddPCR). Cancer Genomics Proteomics15: 299-312 (2018)
  • Hagelgans, A, Jandeck, C, Friedemann, M, Donchin, A, Richter, S and Menschikowski, M. Identification of CpG Sites of SERPINA5 Promoter with Opposite Methylation Patterns in Benign and Malignant Prostate Cells. Anticancer Res37: 6609-6618 (2017)