Metabolic Control

• von Renesse J, Mirtschink P. Ectodysplasin A2 receptor-NF-κB-inducing kinase axis: a new player in muscle wasting to cancer cachexia. Signal Transduction and Targeted Therapy8: 383 (2023)

• Mirtschink P, Neumeister V, Menschikowski M, Suliman R, Wolf G, Kade J, Tiebel O, Poitz DM. 2nd generation of soluble transferrin receptor assay – Consequences for the interpretation of the ‘Thomas’ plot. Journal of Laboratory Medicine47: 275-278 (2023)
• Perakakis N, Harb H, Hale BG, Varga Z, Steenblock C, Kanczkowski W, Alexaki VI, Ludwig B, Mirtschink P, Solimena M, Toepfner N, Zeissig S, Gado M, Abela IA, Beuschlein F, Spinas GA, Cavelti-Weder C, Gerber PA, Huber M, Trkola A, Puhan MA, Wong WW, Linkermann A, Mohan V, Lehnert H, Nawroth P, Chavakis T, Mingrone G, Wolfrum C, Zinkernagel AS, Bornstein SR. Mechanisms and clinical relevance of the bidirectional relationship of viral infections with metabolic diseases. Lancet Diabetes & Endocrinology11: 675-693 (2023)
• von Renesse J, von Bechtolsheim F, Jonas S, Seifert L, Alves TC, Seifert AM, Komorek F, Tritchkova G, Menschikowski M, Bork U, Meisterfeld R, Distler M, Chavakis T, Weitz J, Funk AM#, Kahlert C#, Mirtschink P#. Tumour catabolism independent of malnutrition and inflammation in upper GI cancer patients revealed by longitudinal metabolomics. Journal of Cachexia, Sarcopenia & Muscle14: 298-309 (2023)
• Bischof C#, Mirtschink P#, Yuan T, Wu M, Zhu C, Kaur J, Pham MD, Gonzalez-Gonoggia S, Hammer M, Rogg EM, Sharma R, Bottermann K, Gercken B, Hagag E, Berthonneche C, Sossalla S, Stehr SN, Maxeiner J, Duda MA, Latreille M, Zamboni N, Martelli F, Pedrazzini T, Dimmeler S, Krishnan J. Mitochondrial-cell cycle cross-talk drives endoreplication in heart disease. Science Translational Medicine13: eabi7964.K (2021)
• Kalafati L, Kourtzelis I, Schulte-Schrepping J, Li X, Hatzioannou A, Grinenko T, Hagag E, Sinha A, Has C, Dietz S, Jesus Domingues AM, Nati M, Sormendi S, Neuwirth A, Chatzigeorgiou A, Ziogas A, Lesche N, Dahl A, Ian H, Subramanian P, Wielockx B , Murray P, Mirtschink P, Chung KJ, Schultze JL, Netea MG, Hajishengallis G, Verginis P, Mitroulis I, Chavakis T. Innate immune training of granulopoiesis promotes anti-tumor activity. Cell183: 771–785 (2020)
• Mirtschink, P, Bischof, C, Pham, M D, Sharma, R, Khadayate, S, Rossi, G, Fankhauser, N, Traub, S, Sossalla, S, Hagag, E, Berthonneche, C, Sarre, A, Stehr, S N, Grote, P, Pedrazzini, T, Dimmeler, S, Krek, W and Krishnan, J. Inhibition of the Hypoxia-Inducible Factor 1alpha-Induced Cardiospecific HERNA1 Enhance-Templated RNA Protects From Heart Disease. Circulation139: 2778-2792 (2019)
• Mirtschink, P, Jang, C, Arany, Z and Krek, W. Fructose metabolism, cardiometabolic risk, and the epidemic of coronary artery disease. Eur Heart J39: 2497-2505 (2018)
• Mitroulis, I, Ruppova, K, Wang, B, Chen, L S, Grzybek, M, Grinenko, T, Eugster, A, Troullinaki, M, Palladini, A, Kourtzelis, I, Chatzigeorgiou, A, Schlitzer, A, Beyer, M, Joosten, L A B, Isermann, B, Lesche, M, Petzold, A, Simons, K, Henry, I, Dahl, A, Schultze, J L, Wielockx, B, Zamboni, N, Mirtschink, P, Coskun, U, Hajishengallis, G, Netea, M G and Chavakis, T. Modulation of Myelopoiesis Progenitors Is an Integral Component of Trained Immunity. Cell172: 147-161 e12 (2018)
• Mirtschink, P, Krishnan, J, Grimm, F, Sarre, A, Horl, M, Kayikci, M, Fankhauser, N, Christinat, Y, Cortijo, C, Feehan, O, Vukolic, A, Sossalla, S, Stehr, S N, Ule, J, Zamboni, N, Pedrazzini, T and Krek, W. HIF-driven SF3B1 induces KHK-C to enforce fructolysis and heart disease. Nature522: 444-449 (2015)
• Krishnan, J, Danzer, C, Simka, T, Ukropec, J, Walter, K M, Kumpf, S, Mirtschink, P, Ukropcova, B, Gasperikova, D, Pedrazzini, T and Krek, W. Dietary obesity-associated Hif1alpha activation in adipocytes restricts fatty acid oxidation and energy expenditure via suppression of the Sirt2-NAD+ system. Genes Dev26: 259-70 (2012)

#equal authorship