Publications

Publications 202 4 | Abstracts 202 4
Publications 202 3 | Abstercts 202 3
Publications 2022 | Abstracts 2022
Publications 2021 | Abstracts 2021
Publications 2020 | Abstracts 2020
Publications 2019 | Abstracts 2019
Publications 2018 | Abstracts 2018
Publications 2017 | Abstracts 2017
Publications 2016 | Abstracts 2016
Publications 2015 | Abstracts 2015
Publications 2014 | Abstracts 2014
Publications 2013 | Abstracts 2013
Publications 2012 | Abstracts 2012
Publications 2011 | Abstracts 2011
Publications 2010 | Abstracts 2010
Publications 2009 | Abstracts 2009
Publications 2008 | Abstracts 2008
Publications 2007 | Abstracts 2007
Publications 2006 | Abstracts 2006
Publications 2005 | Abstracts 2005
Publications 2004 | Abstracts 2004
Publications 2003

Publications 2024

Carstens PS, Brendel H, Villar-Ballesteros ML, Mittag J, Hengst C, Birdir C, Taylor PD, Poston L, Morawietz H (2024)
Characterization of human placental fetal vessels in gestational diabetes mellitus
Pflügers Arch.-Eur. J. Physiol. 2024 Oct 9. doi: 10.1007/s00424-024-03028-6. [https://pubmed.ncbi.nlm.nih.gov/39384641/]

Brendel H, Mittag J, Hofmann A, Hempel H, Giebe S, Diaba-Nuhoho P, Wolk S, Reeps C, Morawietz H, Brunssen C (2024)
NADPH Oxidase 4: Crucial for Endothelial Function under Hypoxia—Complementing Prostacyclin
Antioxidants 13(10):1178. doi: 10.3390/antiox13101178. [https://pubmed.ncbi.nlm.nih.gov/39456432/]

Diaba-Nuhoho P, Mittag J, Brunssen C, Morawietz H, Brendel H (2024)
The Vascular Function of Resistance Arteries Depends on NADPH Oxidase 4 and Is Exacerbated by Perivascular Adipose Tissue
Antioxidants 13:503. doi: 10.3390/antiox13050503. [https://pubmed.ncbi.nlm.nih.gov/38790608/]

Adu-Gyamfi M, Goettsch C, Kamhieh-Milz J, Chen L, Pfefferkorn AM, Hofmann A, Brunssen C, Müller G, Walther T, Ashraf MI, Morawietz H, Witowski J, Catar R (2024)
The Role of NOX2-Derived Reactive Oxygen Species in the Induction of Endothelin-Converting Enzyme-1 by Angiotensin II
Antioxidants 13:500. doi: 10.3390/antiox13040500. [https://pubmed.ncbi.nlm.nih.gov/38671948/]

Schubert U, Lehmann S, Schmid J, Morawietz H, Bornstein SR, Ludwig B (2024)
The adrenal gland and pancreatic islets - A beneficial endocrine alliance
Horm. Metab. Res. 56(4):286-293. doi: 10.1055/a-2256-6344. [https://pubmed.ncbi.nlm.nih.gov/38471570/]

Abstracts 2024

Morawietz H, Kamhieh-Milz J, Goettsch C, Chen L, Zickler D, Hofmann A, Brunssen C, Mueller G, Ziegler CG, Catar RA (2024)
Cross-talk between oxidized LDL, oxidative stress and renin-angiotensin-aldosterone system: Impact on endothelial function and atherosclerosis
International Vascular Biology Meeting (IVBM), 2-5 July 2024, Amsterdam, Cvent Events App, Program, Poster Number:05.156

Villar Ballesteros ML, Brendel H, Carstens P, Effenberger D, Mittag J, Giebe S, Taylor PD, Morawietz H (2024)
FABP4 as possible indicator for GDM-induced fetal endothelial dysfunction
Frontiers in CardioVascular Biomedicine 2024, 12-14 April 2024, Amsterdam, Programme: P275, https://esc365.escardio.org/Frontiers-in-Cardiovascular-Biomedicine/programme Cardiovasc. Res. 120 (Suppl. 1, SI): cvae088.19. https://doi.org/10.1093/cvr/cvae088.193

Catar R, Kamhieh-Milz J, Goettsch C, Chen L, Zickler D, Taye A, Hofmann A, Brunssen C, Müller G, Cybularz M, Lehmann S, Schubert U, Ludwig B, Ziegler C, Bornstein S, Krug A, Walther T, Moll G, Morawietz H (2024)
Cross-talk between oxidized LDL, oxidative stress and renin-angiotensin-aldosterone system: Impact on endothelial function and atherosclerosis
67. Deutscher Kongress für Endokrinologie, 6-8 March 2024, Rostock, Programme:71 (Abstract-ID: P02-LB-05)

Publications 2023

Ran X, Müller S, Brunssen C, Huhle R, Scharffenberg M, Schnabel C, Koch T, Gama de Abreu M, Morawietz H, Ferreira JMC, Wittenstein J (2023)
Modulation of the hippo-YAP pathway by cyclic stretch in rat type 2 alveolar epithelial cells-a proof-of-concept study
Front. Physiol. 14:1253810; doi: 10.3389/fphys.2023.1253810 [https://pubmed.ncbi.nlm.nih.gov/37877098/]

Pun SH, O‘Neill KM, Edgar KS, Gill EK, Moez A, Naderi-Meshkin H, Malla SB, Hookham MB, Alsaggaf M, Madishetti VV, Botezatu B, King W, Brunssen C, Morawietz H, Dunne PD, Brazil DP, Medina RJ, Watson CJ, Grieve DJ (2023)
PLAC8-mediated activation of NOX4 signalling restores angiogenic function of endothelial colony-forming cells in experimental hypoxia
Cells 12(18):2220; doi.org/10.3390/cells12182220 [https://pubmed.ncbi.nlm.nih.gov/37759443/]

Morawietz H, Brendel H, Diaba-Nuhoho P, Catar R, Perakakis N, Wolfrum C, Bornstein SR (2023)
Cross-Talk of NADPH Oxidases and Inflammation in Obesity
Antioxidants 12(8):1589. https://doi.org/10.3390/antiox12081589 [https://pubmed.ncbi.nlm.nih.gov/37627585/]

Hofmann A, Khorzom Y, Klimova A, Wolk S, Busch A, Sabarstinski P, Müglich M, Egorov D, Kopaliani I, Poitz DM, Kapalla M, Hamann B, Frank F, Jänichen C, Brunssen C, Morawietz H, Reeps C (2023)
Associations of Tissue and Soluble LOX-1 with Human Abdominal Aortic Aneurysm
J. Am. Heart Assoc. 12:e027537. doi: 10.1161/JAHA.122.027537. [https://pubmed.ncbi.nlm.nih.gov/37421287/]

Morawietz H (2023)
Smoke on the blood stream: Novel insights in cigarette smoke-induced atherosclerosis and plaque erosion
Cardiovasc. Res. 119(9):1781-1783. doi: 10.1093/cvr/cvad097. [https://pubmed.ncbi.nlm.nih.gov/37392427/]

Kamhieh-Milz J, Chen L, Goettsch C, Pfefferkorn AM, Hofmann A, Brunssen C, Müller G, Walther T, Ashraf MI, Moll G, Morawietz H, Witowski J, Catar R (2023)
Angiotensin II promotes endothelin 1 production by regulating NOX2 activity through transcription factor Oct-1
Arterioscler. Thromb. Vasc. Biol. 43(8):1429-1440. doi: 10.1161/ATVBAHA.122.318764. [https://pubmed.ncbi.nlm.nih.gov/37381986/]

Morawietz H (2023)
Identification of a novel redox switch between metabolism and cardiac function using HyPer power
Pflugers Arch.-Eur. J. Physiol. 475(8):907–909. doi: 10.1007/s00424-023-02832-w. [https://pubmed.ncbi.nlm.nih.gov/37353560/]

Klein J, Diaba-Nuhoho P, Giebe S, Brunssen C, Morawietz H (2023)
Regulation of endothelial function by cigarette smoke and next generation tobacco and nicotine products
Pflugers Arch.-Eur. J. Physiol. 475(7):835-844. doi: 10.1007/s00424-023-02824-w [https://pubmed.ncbi.nlm.nih.gov/37285061/]

Hamann B, Klimova A, Klotz F, Frank F, Jänichen C, Kapalla M, Sabarstinski P, Wolk S, Morawietz H, Poitz DM, Hofmann A, Reeps C (2023)
Regulation of CD163 Receptor in Patients with Abdominal Aortic Aneurysm and Associations with Antioxidant Enzymes HO-1 and NQO1
Antioxidants 12(4):947. doi.org/10.3390/antiox12040947. [https://pubmed.ncbi.nlm.nih.gov/37107322/]

Giebe S, Brux M, Hofmann A, Lowe F, Breheny D, Morawietz H, Brunssen C (2023)
Comparative study of the effects of cigarette smoke versus next generation tobacco and nicotine product extracts on inflammatory biomarkers of human monocytes
Pflugers Arch.-Eur. J. Physiol. 475(7):823-833. doi: 10.1007/s00424-023-02809-9. [https://pubmed.ncbi.nlm.nih.gov/37081240/

Amponsah-Offeh M, Diaba-Nuhoho P, Speier S, Morawietz H (2023)
Oxidative stress, Antioxidants and Hypertension
Antioxidants 12(2):281. https://doi.org/10.3390/antiox12020281. [https://pubmed.ncbi.nlm.nih.gov/36829839/]

Tolkmitt J, Brendel H, Zatschler B, Brose S, Brunssen C, Kopaliani I, Deussen A, Matschke K, Morawietz H (2023)
Aprotinin does not Impair Vascular Function in Patients Undergoing Coronary Artery Bypass Graft Surgery
Horm. Metab. Res. 55(1):65-74. doi: 10.1055/a-1984-0255. [https://pubmed.ncbi.nlm.nih.gov/36599358/]

Abstracts 2023

Jänichen C, Hofmann A, Hamann B, Wolk S, Sabarstinski P, Frank F, Morawietz H, Poitz DM, Reeps C (2023)
Phänotypische und funktionelle Änderungen alternder glatter Gefäßmuskelzellen aus humanen Aortenaneurysmen
39. Jahrestagung der Deutschen Gesellschaft für Gefäßchirurgie und Gefäßmedizin, Osnabrück, 27.–30.09.2023, Abstractband:160 (Abstract FV157)

Frank F, Hofmann A, Klimova A, Hamann B, Sabarstinski P, Wolk S, Poitz DM, Morawietz H, Reeps C (2024)
Assoziation von NADPH-Oxidase 4 mit Merkmalen der Stabilität arteriosklerotischer Plaques in Patienten mit asymptomatischer Carotisstenose
39. Jahrestagung der Deutschen Gesellschaft für Gefäßchirurgie und Gefäßmedizin, Osnabrück, 27.–30.09.2023, Abstractband:159 (Abstract FV156)

Frank F, Hofmann A, Hamann B, Egorov D, Kopaliani I, Wolk S, Poitz D, Morawietz H, Schröder K, Reeps C (2024)
NADPH-Oxidase 4 wirkt protektiv bei Carotisstenose
26. Chirurgische Forschungstage, Mannheim, 21.-22.09.2023, Programm und Abstracts:77 (Abstract ID: 63692), https://www.umm.de/docs/klinikum/chirurgie/Chirurgische-Forschungstage-2023_Programm.pdf

Diaba-Nuhoho P, Brunssen C, Morawietz H, Brendel H (2023)
NADPH oxidase 4 and endothelium-derived hyperpolarization factor play a role in maintaining vascular function in small resistance arteries
European Society for Microcirculation Conference, Aarhus, Denmark, J. Vasc. Res. 60 (Suppl. 1):56 (Abstract 94). https://doi.org/10.1159/000533846

Morawietz H, Frenzel A, Mieting A, Goettsch W, Valtink M, Roehlecke C, Jaszai J, Funk RHW, Becker KA, Engelmann K (2023)
Induction of VEGF-A_165a by high glucose in human retinal and endothelial cells and VEGF concentration in vitreous fluid of diabetic patients
European Society for Microcirculation Conference, Aarhus, Denmark, J. Vasc. Res. 60 (Suppl. 1):40 (Abstract 62). https://doi.org/10.1159/000533846

Tolkmitt J, Brendel H, Zatschler B, Brose S, Brunssen C, Kopaliani I, Deussen A, Matschke K, Morawietz H (2023)
Aprotinin does not impair vascular function in patients undergoing coronary artery bypass graft surgery
European Society for Microcirculation Conference, Aarhus, Denmark, J. Vasc. Res. 60 (Suppl. 1):38 (Abstract 58). https://doi.org/10.1159/000533846

Al Arawe N, Kamhieh-Milz J, Chen L, Goettsch C, Pfefferkorn AM, Hofmann A, Brunssen C, Mueller G, Walther T, Imtiaz Ashraf M, Moll G, Morawietz H, Witowski J, Catar R (2023)
Angiotensin II Promotes Endothelin 1 Production by Regulating NOX2 Activity Through Transcription Factor Oct-1
European Society for Microcirculation Conference, Aarhus, Denmark, J. Vasc. Res. 60 (Suppl. 1):18 (Abstract 27). https://doi.org/10.1159/000533846

Al Arawe N, Catar R, Kamhieh-Milz J, Goettsch C, Chen L, Zickler D, Taye A, Hofmann A, Brunssen C, Mueller G, Cybularz M, Lehmann S, Schubert U, Ludwig B, Ziegler C, Bornstein S, Krug A, Walther T, Moll G, Morawietz H (2023)
Oct-1 is a key mediator for angiotensin II- and oxidized LDL-induced upregulation of angiotensin-II type-1 Receptor: New implications for the development of atherosclerosis
European Society for Microcirculation Conference, Aarhus, Denmark, J. Vasc. Res. 60 (Suppl. 1):13 (Abstract 20). https://doi.org/10.1159/000533846526 /000533846

Publications 2022

Morawietz H, Frenzel A, Mieting A, Goettsch W, Valtink M, Roehlecke C, Jászai J, Funk RHW, Becker KA, Engelmann K (2022)
Induction of VEGF-A_165a in human retinal and endothelial cells in response to glyoxal
Ther. Apher. Dial. 26 (Suppl. 1):29-34. doi: 10.1111/1744-9987.13803. [https://pubmed.ncbi.nlm.nih.gov/36468302/]

Ofori EK, Letsu BS, Amponsah SK, Ahenkorah J, Crabbe S, Kwao-Zigah G, Oppong SY, Diaba‑Nuhoho P, Amanquah SD (2022)
Impact of blood perilipin A levels on obesity and metabolic health
BMC Research Notes (2022) 15(1):367. doi: 10.1186/s13104-022-06261-3. [https://pubmed.ncbi.nlm.nih.gov/36503541/]

Hofmann A, Frank F, Wolk S, Busch A, Klimova A, Sabarstinski P, Gerlach M, Egorov D, Kopaliani I, Weinert S, Hamann B, Poitz DM, Brunssen C, Morawietz H, Schröder K, Reeps (2022)
NOX4 mRNA correlates with plaque stability in patients with carotid artery stenosis
Redox Biol.57:102473. doi: 10.1016/j.redox.2022.102473. [https://pubmed.ncbi.nlm.nih.gov/36182808/]

Hofmann A, Hamann B, Klimova A, Müglich M, Wolk S, Busch A, Frank F, Sabarstinski P, Kapalla M, Nees JA, Brunssen C, Poitz DM, Morawietz H, Reeps C (2022)
Pharmacotherapies and aortic heme oxygenase-1 expression in patients with abdominal aortic aneurysm
Antioxidants 11(9):1753. doi: 10.3390/antiox11091753 [https://pubmed.ncbi.nlm.nih.gov/36139827/]

Evans PC, Davidson SM, Wojta J, Bäck M, Bollini S, Brittan M, Catapano AL, Chaudhry B, Cluitmans M, Gnecchi M, Guzik TJ, Hoefer I, Madonna R, Monteiro JP, Morawietz H, Osto E, Padró T, Sluimer JC, Tocchetti CG, Van der Heiden K, Vilahur G, Waltenberger J, Weber C (2022)
From novel discovery tools and biomarkers to precision medicine - basic cardiovascular science highlights of 2021/2022
Cardiovasc. Res. 118(13):2754-2767. doi: 10.1093/cvr/cvac114[https://pubmed.ncbi.nlm.nih.gov/35899362/]

Julius U, Schatz U, Tselmin S, Morawietz H (2022)
COVID-19 and Lipid Disorders
Horm. Metab. Res. 54(8):514-521. doi: 10.1055/a-1860-2610. [https://pubmed.ncbi.nlm.nih.gov/35835148/]

Rodionov RN, Jarzebska N, Burdin D, Todorov V, Martens-Lobenhoffer J, Hofmann A, Kolouschek A, Cordasic N, Jacobi J, Rubets E, Morawietz H, O'Sullivan JF, Markov AG, Bornstein SR, Hilgers K, Maas R, Pfluecke C, Chen Y, Bode-Böger SM, Hugo CPM, Hohenstein B, Weiss N (2022)
Overexpression of alanine-glyoxylate aminotransferase 2 protects from asymmetric dimethylarginine-induced endothelial dysfunction and aortic remodeling
Sci Rep. 12:9381. doi: 10.1038/s41598-022-13169-2. [https://pubmed.ncbi.nlm.nih.gov/35672381/]

Catar R, Chen L, Zhao H, Wu D, Kamhieh-Milz J, Lücht C, Zickler D, Krug AW, Ziegler CG, Morawietz H, Witowski J (2022)
Native and oxidized low-density lipoproteins increase the expression of the LDL receptor and the LOX-1 receptor, respectively, in arterial endothelial cells
Cells 11(2):204. doi: 10.3390/cells11020204. [https://pubmed.ncbi.nlm.nih.gov/35053320/]

Punch E, Klein J, Diaba-Nuhoho P, Morawietz H, Garelnabi M (2022)
Effects of PCSK9 Targeting: Alleviating Oxidation, Inflammation and Atherosclerosis
J. Am. Heart Assoc. 11:e023328. doi: 10.1161/JAHA.121.023328. [https://pubmed.ncbi.nlm.nih.gov/35048716/]

Abstracts 2022

Morawietz H (2022)
Going with the flow: Regulation of endothelial cell function by shear stress
51. Jahrestagung der Deutschen Gesellschaft für Angiologie, 24.-26. November 2022, Wiesbaden

Diaba-Nuhoho P, Brunssen C, Morawietz H, Brendel H (2022)
NADPH oxidase 4 and endothelium-derived hyperpolarization factor play a role in maintaining vascular function in small resistance arteries
Joint Meeting of the Gesellschaft für Mikrozirkulation und Vaskuläre Biologie e.V. (GfMVB) and the British Microcirculation and Vascular Biology Society (BMVBS), July 7-8, 2022, Berlin, Germany, Abstracts, Poster Nr.:77

Tolkmitt J, Brendel H, Zatschler B, Brose S, Brunssen C, Kopaliani I, Deussen A, Matschke K, Morawietz H (2022)
Serine protease inhibitor aprotinin does not affect vascular function of the internal mammary arteries from patients undergoing coronary artery bypass graft surgery
Clin Res Cardiol (2022): Abstract 1413. DOI: https://doi.org/10.1007/s00392-022-02002-5

Giebe S, Klein J, Brendel H, Matschke K, Kopaliani I, Morawietz H, Brunssen C (2022)
Impact of conventional cigarettes versus tobacco heating products on vascular function ex vivo
Clin Res Cardiol (2022): Abstract 827. DOI: https://doi.org/10.1007/s00392-022-02002-5

Publications 2021

Diaba‑Nuhoho P, Amponsah‑Offeh M (2021)
Reproducibility and research integrity: the role of scientists and institutions
BMC Research Notes 14:451. doi: 10.1186/s13104-021-05875-3. [https://pubmed.ncbi.nlm.nih.gov/34906213/]

Diaba‑Nuhoho P, Cour M, Hadebe N, Marais D, Lecour S, Blackhurst D (2021)
Chronic and moderate consumption of reduced‑alcohol wine confers cardiac benefits in a rat model of pulmonary arterial hypertension
BMC Research Notes 14:324. doi: 10.1186/s13104‑021‑05738‑x. [https://pubmed.ncbi.nlm.nih.gov/34425891/]

Catar R, Moll G, Kamhieh-Milz J, Luecht C, Chen L, Zhao H, Ernst L, Willy K, Girndt M, Fiedler R, Witowski J, Morawietz H, Ringdén O, Dragun D, Eckardt KU, Schindler R, Zickler D (2021)
Expanded Hemodialysis Therapy Ameliorates Uremia-Induced Systemic Microinflammation and Endothelial Dysfunction by Modulating VEGF, TNF-α and AP-1 Signaling
Front Immunol. 2021 Nov 11;12:774052. doi: 10.3389/fimmu.2021.774052. eCollection 2021.[https://pubmed.ncbi.nlm.nih.gov/34858433/]

Brendel H (2021)
[Sports protects by oxygen radicals]
Cardio News 24 (10):37 [https://www.kardiologie.org/cardionews/39692]

Hofmann A, Müglich M, Wolk S, Khorzom Y, Sabarstinski P, Kopaliani I, Egorov D, Horn F, Brunssen C, Giebe S, Hamann B, Deussen A, Morawietz H, Poitz DM, Reeps C (2021)
Induction of heme oxygenase-1 is linked to the severity of disease in human abdominal aortic aneurysm
J. Am. Heart Assoc. 2021 Oct 8;e022747. doi: 10.1161/JAHA.121.022747. Online ahead of print [https://pubmed.ncbi.nlm.nih.gov/34622673/]

Hofmann A, Brunssen C, Peitzsch M, Mittag J, Frenzel A, Eisenhofer G, Brown NF, Weldon SM, Reeps C, Bornstein SR, Morawietz H (2021)
Impact of Dietary Sodium Reduction on the Development of Obesity and Type 2 Diabetes in db/db Mice
Horm. Metab. Res. 53(10):699-704. doi: 10.1055/a-1625-6296. [https://pubmed.ncbi.nlm.nih.gov/34607368/]

Giebe S, Hofmann A, Brux M, Lowe F, Breheny D, Morawietz H, Brunssen C (2021)
Comparative study of the effects of cigarette smoke versus next generation tobacco and nicotine product extracts on endothelial function
Redox Biol. 47:102150. doi: 10.1016/j.redox.2021.102150. [https://pubmed.ncbi.nlm.nih.gov/34601427/]

Brock T, Boudriot E, Klawitter A, Großer M, Nguyen TTP, Giebe S, Klapproth E, Temme A, El-Armouche A, Breier G (2021)
The Influence of VE-Cadherin on Adhesion and Incorporation of Breast Cancer Cells into Vascular Endothelium
Int. J. Mol. Sci. 22(11):6049. doi: 10.3390/ijms22116049 [https://pubmed.ncbi.nlm.nih.gov/34205118/]

Bornstein SR, Guan K, Brunßen C, Mueller G, Kamvissi-Lorenz V, Lechler R, Trembath R, Mayr M, Poston L, Sancho R; IRTG 2251, IRTG Study Group: Ahmed S, Alfar E, Aljani B, Alves TC, Amiel S,, Andoniadou CL, Bandral M, Belavgeni A, Berger I, Birkenfeld A, Bonifacio E, Chavakis T, Chawla P, Choudhary P, Cujba AM, Delgadillo Silva LF, Demcollari T, Drotar DM, Duin S, El-Agroudy NN, El-Armouche A, Eugster A, Gado M, Gavalas A, Gelinsky M, Guirgus M, Hansen S, Hanton E, Hasse M, Henneicke H, Heller C, Hempel H, Hogstrand C, Hopkins D, Jarc L, Jones PM, Kamel M, Kämmerer S, King AJF, Kurzbach A, Lambert C, Latunde-Dada Y, Lieberam I, Liers J, Li JW, Linkermann A, Locke S, Ludwig B, Manea T, Maremonti F, Marinicova Z, McGowan BM, Mickunas M, Mingrone G, Mohanraj K, Morawietz H, Ninov N, Peakman M, Persaud SJ, Pietzsch J, Cachorro E, Pullen TJ, Pyrina I, Rubino F, Santambrogio A, Schepp F, Schlinkert P, Scriba LD, Siow R, Solimena M, Spagnoli FM, Speier S, Stavridou A, Steenblock C, Strano A, Taylor P, Tiepner A, Tonnus W, Tree T, Watt F, Werdermann M, Wilson M, Yusuf N, Ziegler CG (2021)
The transCampus Metabolic Training Programme Explores the Link of SARS-CoV-2 Virus to Metabolic Disease
Horm. Metab. Res. 53:204-206. doi: 10.1055/a-1377-6583. [https://pubmed.ncbi.nlm.nih.gov/33652492/]

Willmes DM, Daniels MA, Kurzbach A, Lieske S, Bechmann N, Schumann T, Henke C, Kurzbach A, El-Agroudy NN, da Costa Goncalves AC, Peitzsch M, Hofmann A, Kanczkowski W, Kräker K, Müller DN, Morawietz H, Deussen A, Wagner M, El-Armouche A, Helfand SL, Bornstein SR, de Cabo R, Bernier M, Eisenhofer G, Tank J, Jordan J, Birkenfeld AL (2021)
The longevity gene mIndy (I’m Not Dead, Yet) affects blood pressure through sympathoadrenal mechanisms
JCI Insight. 6(2):136083. doi: 10.1172/jci.insight.136083. [https://pubmed.ncbi.nlm.nih.gov/33491666/]

Werdermann M, Berger I, Scriba LD, Santambrogio A, Schlinkert P, Brendel H, Morawietz H, Schedl A, Peitzsch M, King AJF, Andoniadou CL, Bornstein SR, Steenblock C (2021)
Insulin and obesity transforms hypothalamic-pituitary-adrenal axis stemness and function in a hyperactive state
Mol. Metab. 43:101112. doi: 10.1016/j.molmet.2020.1011122020. [https://pubmed.ncbi.nlm.nih.gov/33157254/]

Abstracts 2021

Brendel H, Tolkmitt J, Zatschler B, Brunssen C, Brose S, Kopaliani I, Deussen A, Matschke K, Morawietz H (2021)
Serine protease inhibitor aprotinin does not affect vascular function of the internal mammary artery from patients undergoing coronary bypass surgery
Joint Vascular Biology meeting of German Society for Microcirculation and Vascular Biology and Netherlands Vascular Biology Organization, 3-5 November 2021, Göttingen, Poster, https://gfmvb.com/?page_id=340#page-content

Giebe S, Klein J, Hofmann A, Brux M, Lowe F, Breheny D, Morawietz H, Brunssen C (2021)
Comparative study of the effects of cigarette smoke versus next generation tobacco and nicotine product extracts on endothelial function
Joint Vascular Biology meeting of German Society for Microcirculation and Vascular Biology and Netherlands Vascular Biology Organization, 3-5 November 2021, Göttingen, Poster, https://gfmvb.com/?page_id=340#page-content

Diaba-Nuhoho P, Brunssen C, Morawietz H, Brendel H (2021)
NADPH oxidase 4 and endothelium-derived hyperpolarization factor can maintain vascular function in small resistance arteries
100^th Annual Meeting of the German Physiological Society 2021, Frankfurt, Book of Abstracts:463 (B 10-10)

Diaba-Nuhoho P, Shahid A, Brunssen C, Morawietz H, Brendel H (2021)
NADPH oxidase 4 has a crucial impact on the microcirculation of hypercholesteremic LDL receptor deficient mice
Eur. Heart J., 42 (Suppl 1) ESC Congress 2021 - The Digital Experience 27-30 August 2021, Abstract Supplement: ehab724.3381, http://doi.org/10.1093/eurheartj/ehab724.3381

Diaba-Nuhoho P, Brunssen C, Morawietz H, Brendel H (2021)
NOX4 and endothelium-derived hyperpolarization factor in small resistance arteries
EVBO/ESM Online Summer School, 13-15th July 2021, Organizers: Mauro Siragusa (Frankfurt), Paola Campagnolo (Surrey), Fiona Wilkinson (Manchester), Graeme Birdsey (London), Jaap van Buul (Amsterdam), Henning Morawietz (Dresden)
EVBO/ESM Online Summer School, 13-15th July 2021, https://evbo.org/summer-school-2/, Flash talk 7 (14 July 2021)

Diaba-Nuhoho P, Shahid A, Brunssen C, Morawietz H, Brendel H (2021)
NADPH oxidase 4 has a crucial impact on the microcirculation of hypercholesteremic LDL receptor deficient mice
European Society for Microcirculation Online Meeting 2021, 27 May 2021, Organizers: Prof. Christian Alkjaer (Aarhus), Prof. Cor de Wit (Lübeck), Prof. Henning Morawietz (Dresden), Prof. Jo De Mey (Maastricht), Prof. Nicola J. Brown (Sheffield), Prof. Ulf Simonsen (Aarhus), Prof. Ylva Hellsten (Copenhagen)
European Society for Microcirculation Online Meeting 27 May 2021, Abstracts: https://conferences.au.dk/esm/, Abstract: 38 (ME7)

Diaba-Nuhoho P, Brendel H, Brunssen C, Morawietz H (2021)
Perivascular adipose tissue and NADPH oxidase 4 can maintain aortic vascular function in LDL receptor deﬁcient mice
Joint virtual meeting of the 13th ISFA World Congress and the 3rd E-ISFA Congress, March 17-20, 2021, Program: https://eventclass.org/contxt_eisfa2021/welcome/index, Abstract #81 (P-16)

Morawietz H, Frenzel A, Mieting A, Göttsch W, Valtink M, Roehlecke C, Jaszai J, Funk RHW, Becker KA, Engelmann K (2021)
Induction of VEGF-A 165A in human retinal and endothelial cells in response to high glucose and VEGF concentrations in the vitreous ﬂuid of patients with type 2 diabetes
Joint virtual meeting of the 13th ISFA World Congress and the 3rd E-ISFA Congress, March 17-20, 2021, Program: https://eventclass.org/contxt_eisfa2021/welcome/index, Abstract #99 (P-19)

Hofmann A, Brunssen C, Peitzsch M, Mittag J, Frenzel A, Eisenhofer G, Brown N, Weldon SM, Bornstein SR, Morawietz H (2021)
Reducing dietary sodium does not aﬀect development of obesity and type 2 diabetes in db/db mice
Joint virtual meeting of the 13th ISFA World Congress and the 3rd E-ISFA Congress, March 17-20, 2021, Program: https://eventclass.org/contxt_eisfa2021/welcome/index, Abstract #102 (P-20)

Publications 2020

Werdermann M, Berger I, Scriba LD, Santambrogio A, Schlinkert P, Brendel H, Morawietz H, Schedl A, Peitzsch M, King AJF, Andoniadou CL, Bornstein SR, Steenblock C (2020)
Insulin and obesity transforms hypothalamic-pituitary-adrenal axis stemness and function in a hyperactive state
Mol. Metab. 2020 Nov 3:101112. doi: 10.1016/j.molmet.2020.101112. Online ahead of print.[https://pubmed.ncbi.nlm.nih.gov/33157254/]

Santovito D, Egea V, Bidzhekov K, Natarelli L, Mourão A, Blanchet X, Wichapong K, Aslani M, Brunßen C, Horckmans M, Hristov M, Geerlof A, Lutgens E, Daemen MJAP, Hackeng T, Ries C, Chavakis T, Morawietz H, Naumann R, von Hundelshausen P, Steffens S, Duchêne J, Megens RTA, Sattler M, Weber C (2020)
Autophagy unleashes noncanonical microRNA functions
Autophagy, 2020 Oct 15;1-3. doi: 10.1080/15548627.2020.1830523. Online ahead of print. [https://pubmed.ncbi.nlm.nih.gov/33054575/]

Morawietz H, Julius U, Bornstein SR (2020)
Cardiovascular diseases, lipid-lowering therapies and European registries in the COVID-19 pandemic?
Cardiovasc. Res. 116:e122-e125. doi:10.1093/cvr/cvaa176 [https://pubmed.ncbi.nlm.nih.gov/32678443/]

Bornstein SR, Voit-Bak K, Schmidt D, Morawietz H, Bornstein AB, Balanzew W, Julius U, Rodionov RN, Biener AM, Wang J, Schulte KM, Krebs P, Vollmer G, Straube R (2020)
Is there a role for environmental and metabolic factors predisposing to severe COVID-19?
Horm. Metab. Res. 52:540-546. doi: 10.1055/a-1182-2016 [https://pubmed.ncbi.nlm.nih.gov/32599638/]

Santovito D, Egea V, Bidzhekov K, Natarelli L, Mourão A, Blanchet X, Wichapong K, Aslani M, Brunßen C, Horckmans M, Hristov M, Geerlof A, Lutgens E, Daemen MJAP, Hackeng T, Ries C, Chavakis T, Morawietz H, Naumann R, von Hundelshausen P, Steffens S, Duchêne J, Megens RTA, Sattler M, Weber C (2020)
Noncanonical inhibition of caspase-3 by a nuclear microRNA confers endothelial protection by autophagy in atherosclerosis
Sci. Transl. Med. 12(546):eaaz2294 (1-15). doi: 10.1126/scitranslmed.aaz2294 [https://pubmed.ncbi.nlm.nih.gov/32493793/]

Hofmann A, Brunssen C, Wolk S, Reeps C, Morawietz H (2020)
Soluble LOX-1: A Novel Biomarker in Patients With Coronary Artery Disease, Stroke, and Acute Aortic Dissection?
J. Am. Heart Assoc. 9(1):e013803. DOI: 10.1161/JAHA.119.013803 [https://www.ncbi.nlm.nih.gov/pubmed/31902328]

Brendel H, Shahid A, Hofmann A, Mittag J, Bornstein SR, Morawietz H, Brunssen C (2020)
NADPH oxidase 4 mediates the protective effects of physical activity against obesity-induced vascular dysfunction
Cardiovasc. Res. 116:1767-1778. doi: 10.1093/cvr/cvz322 [https://www.ncbi.nlm.nih.gov/pubmed/31800011]

Rojo Arias JE, Economopoulou M, Juárez López DA, Kurzbach A, Au Yeung KH, Englmaier V, Merdausl M, Schaarschmidt M, Ader M, Morawietz H, Funk RH, Jászai J (2020)
VEGF-Trap is a potent modulator of vasoregenerative responses and protects dopaminergic amacrine network integrity in degenerative ischemic neovascular retinopathy
J. Neurochem.,153:390-412. doi: 10.1111/jnc.14875 [https://www.ncbi.nlm.nih.gov/pubmed/31550048]

O’Neill KM, Campbell DC, Edgar KS, Gill EK, Moez A, McLoughlin KJ, O’Neill CL, Dellett M, Hargey CJ, Abudalo RA, O’Hare M, Doyle P, Toh T, Khoo J, Wong J, McCrudden CM, Meloni M, Brunssen C, Morawietz H, Yoder MC, McDonald DM, Watson CJ, Stitt AW, Margariti A, Medina RJ, Grieve DJ (2020)
NOX4 is a major regulator of cord blood-derived endothelial colony-forming cells which promotes post-ischaemic revascularization
Cardiovasc. Res. 116:393-405. doi:10.1093/cvr/cvz090 [https://www.ncbi.nlm.nih.gov/pubmed/30937452]

Abstracts 2020

Hofmann A, Müglich M, Wolk S, Poitz D, Brunssen C, Morawietz H, Reeps C (2020)
Upregulation of Heme Oxygenase-1 is Associated With Inflammation in Patients With Abdominal Aortic Aneurysms
American Heart Association's Scientific Sessions on Vascular Discovery - From Genes to Medicine Arterioscler. Thromb. Vasc. Biol. 40 (1):A416

Giebe-Pohling S, Hofmann A, Brux M, Lowe F, Breheny D, Morawietz H, Brunßen C (2020)
Impact of cigarette smoke compared to next generation tobacco and nicotine products on endothelial function
Clin. Res. Cardiol. 109 (Suppl 1):P1900, DOI: 10.1007/s00392-020-01621-0

Brendel H, Shahid A, Mittag J, Bornstein SR,Morawietz H, Brunßen C (2020)
NADPH oxidase 4 mediates the protective effects of physical activity against obesity-induced vascular dysfunction
Clin. Res. Cardiol. 109 (Suppl 1):P1565, DOI: 10.1007/s00392-020-01621-0

Morawietz H (2020)
Impact of shear stress on endothelial function
International Cell Culture Under Flow Meeting 2020, February 18-19, 2020. Biomedical Center Munich, Germany, Abstract Book:11

Publications 2019

Morawietz H (2019)
Oxidative stress and endothelial function: Early sign or detection of risk factors for hypertension and cardiovascular diseases
MHT (Hungarian Society of Hypertension) Hírmondó, 2019, September 20:4

Riedel K, Deussen AJ, Tolkmitt J, Weber S, Schlinkert P, Zatschler B, Friebel C, Müller B, El-Armouche A, Morawietz H, Matschke K, Kopaliani I (2019)
Estrogen determines sex differences in adrenergic vessel tone by regulation of endothelial β-adrenoceptor expression
Am. J. Physiol. Heart Circ. Physiol. 317: H243-H254 [https://www.ncbi.nlm.nih.gov/pubmed/31149843]

Siow RC, Morawietz H (2019)
Vascular networking for the young at heart: Joint European Summer School for microcirculation and vascular biology
Cardiovasc. Res. 115:e49-e51. doi: 10.1093/cvr/cvz054 [https://www.ncbi.nlm.nih.gov/pubmed/30796803]

Morawietz H (2019)
Recent Cardiovascular Research highlights from Europe
Cardiovasc. Res. 115:e9–e11. doi:10.1093/cvr/cvy240 [https://www.ncbi.nlm.nih.gov/pubmed/30576434]

Abstracts 2019

Giebe-Pohling S, Hofmann A, Brux M, Lowe F, Breheny D, Morawietz H, Brunssen C (2019)
Impact of cigarette smoke compared to next generation tobacco and nicotine products on endothelial function
26^th Annual Meeting of the Society for Redox Biology and Medicine (SfRBM), November 20-23, 2019, Las Vegas, NV, USA
Free Radic. Biol. Med. 145 (Suppl 1):S109 (Abstract 247)

Langbein H, Shahid A, Hofmann A, Mittag J, Bornstein SR,Morawietz H, Brunßen C (2019)
Protective effects of exercise on vascular function are mediated by NADPH oxidase 4
41^st Annual Meeting of the German Society for Microcirculation and Vascular Biology (GfMVB), Heidelberg, Germany, Abstract book:6

Diaba-Nuhoho P, Langbein H, Brunssen C Morawietz H (2019)
NADPH oxidase 4 is dispensable for perivascular adipose tissue mediated endothelial function in conductance arteries
98^th Annual Meeting of the German Physiological Society 2019, Ulm
Acta Physiol. (Oxf.) 227 (Suppl 719):145 (A11-07)

Morawietz H (2019)
Oxidative stress and endothelial function: Early sign or detection of risk factors for hypertension and cardiovascular diseases
27^th Annual Congress of the Hungarian Society of Hypertension ESH-HSH Joint Symposium, September 19-21, 2019, Siofok, Hungary
Program & Abstracts

Morawietz H (2019)
Oxidative stress and endothelial function: Impact on cardiovascular diseases
The 2^nd International Qi-Blood Conference, Joint Meeting of Chinese-Japanese TCM, Peking University-University of Hong Kong of TCM, September 13-19, 2019, Beijing, China
Program & Abstracts:80-82 (PL-10)

Morawietz H, Langbein H, Shahid A, Hofmann A, Mittag J, Bornstein SR,Brunßen C (2019)
Protective effects of exercise on vascular function are mediated by NADPH oxidase 4
Eur. Heart J., 40 (Suppl 1):(P6285)
Diaba-Nuhoho P, Langbein H, Brunßen C Morawietz H (2019)
NADPH oxidase 4 is dispensable for perivascular adipose tissue mediated endothelial function in conductance arteries
13th CRTD Summer Conference 2019, Dresden:ID40

Shahid A, Langbein H, Brunßen C Morawietz H (2019)
NADPH oxidase 4 mediates cardiac adaptions to exercise
13th CRTD Summer Conference 2019, Dresden:ID37

Langbein H, Shahid A, Hofmann A, Mittag J, Bornstein SR,Morawietz H, Brunßen C (2019)
Protective effects of exercise on vascular function are mediated by NADPH oxidase 4
Annual Scientific Meeting and Scientific Sessions of the American Heart Association on Vascular Discovery - From Genes to Medicine (Formerly ATVB|PVD Scientific Sessions, now American Heart Association; Council on Arteriosclerosis, Thrombosis & Vascular Biology; Council on Peripheral Vascular Disease; Council on Genomic & Precision Medicine; Society for Vascular Surgery; Vascular Research Initiative Conference; American Venous Forum), May 14-16, 2019, Boston, MA, Final Program:60 (396)
Arterioscler. Thromb. Vasc. Biol. 39 (1):A396

Almedawar MM, Brux M, Brunßen C, Morawietz H (2019)
Cigarette smoke impairs the anti-oxidative response by reducing heme levels and inducing Bach1
Clin Res Cardiol 108 (Suppl 1):V1763, DOI: 10.1007/s00392-019-01435-9

Langbein H, Shahid A, Hofmann A, Mittag J, Bornstein SR,Morawietz H, Brunßen C (2019)
Protective effects of exercise on vascular function are mediated by NADPH oxidase 4
Clin Res Cardiol 108 (Suppl 1):P1527, DOI: 10.1007/s00392-019-01435-9

Kopaliani I, Riedel K, Tolkmitt J, Weber S, Schlinkert P, El-Armouche A, Morawietz H, Deussen A (2019)
Estrogen determines the sex-differences in adrenergic vessel tone by regulation of endothelial b-adrenoceptor expression

Clin Res Cardiol 108 (Suppl 1):P874, DOI: 10.1007/s00392-019-01435-9
Langbein H, Shahid A, Hofmann A, Mittag J, Bornstein SR,Morawietz H, Brunßen C (2019)
Protective effects of exercise on vascular function are mediated by NADPH oxidase 4
3^rd Joint Meeting of the European-Society-for-Microcirculation (ESM) and the European-Vascular-Biology-Organization (EVBO), April 15-18, 2019, Maastricht, the Netherlands

J. Vasc. Res. 56 (Suppl. 1):100 (216)
Almedawar MM, Brux M, Brunssen C, Morawietz H (2019)
Cigarette smoke impairs the anti-oxidative response by reducing heme levels and inducing Bach1
3^rd Joint Meeting of the European-Society-for-Microcirculation (ESM) and the European-Vascular-Biology-Organization (EVBO), April 15-18, 2019, Maastricht, the Netherlands
J. Vasc. Res. 56 (Suppl. 1):84 (179)

Langbein H, Hofmann A, Shahid A, Mittag J,Morawietz H, Brunßen C (2019)
NADPH oxidase 4 mediates beneficial effects of exercise on vascular function
11^th World Congress for Microcirculation, September 9-13, 2018, Vancouver, BC, Canada
Microcirculation 26:e12524, 88 (WEPE025)

Almedawar MM, Giebe S, Brux M, Brunssen C, Morawietz H (2019)
Cigarette smoke-induced BACH1 regulates the cross talk between NRF2 and AHR through inhibiting microRNA-125b
11^th World Congress for Microcirculation, September 9-13, 2018, Vancouver, BC, Canada
Microcirculation 26:e12524, 77 (TUPE040)

Publications 2018

Schwarz PEH, Timpel P, Harst L, Greaves CJ, Ali MK, Lambert J, Weber MB, Almedawar MM, Morawietz H (2018)
Reprint of: Blood sugar regulation for cardiovascular health promotion and disease prevention - JACC health promotion series
J. Am. Coll. Cardiol. 72(23 Pt B):3071-3086. doi: 10.1016/j.jacc.2018.10.026 [https://www.ncbi.nlm.nih.gov/pubmed/30522637]

Schwarz PEH, Timpel P, Harst L, Greaves CJ, Ali MK, Lambert J, Weber MB, Almedawar MM, Morawietz H (2018)
Blood sugar regulation for cardiovascular health promotion and disease prevention - JACC health promotion series
J. Am. Coll. Cardiol. 72(15):1829-1844. doi: 10.1016/j.jacc.2018.07.081 [https://www.ncbi.nlm.nih.gov/pubmed/30286928]

Almedawar MM, Siow RC, Morawietz H (2018)
MicroRNAs as novel biomarkers in depression, diabetes and cardiovascular diseases
In: “Depression and Type 2 Diabetes” (Ed. by K. Ismail, A. Barthel, S. R. Bornstein, J. Licinio), Oxford University Press, Chapter 3, 25-36, ISBN: 9780198789284 [https://global.oup.com/academic/product/depression-and-type-2-diabetes-9780198789284?cc=de&lang=en&]

Morawietz H (2018)
Cardiovascular protection by Nox4
Cardiovasc. Res. 114:353-355. doi: 10.1093/cvr/cvx252 [https://www.ncbi.nlm.nih.gov/pubmed/29324982]

Hofmann A, Brunssen C, Morawietz H (2018)
Contribution of lectin-like oxidized low-density lipoprotein receptor-1 and LOX-1 modulating compounds to vascular diseases
Vasc. Pharmacol. 107:1-11. doi: http://dx.doi.org/10.1016/j.vph.2017.10.002 [https://www.ncbi.nlm.nih.gov/pubmed/29056472]

Abstracts 2018

Brunssen C, Arsov A, Hempel H, Poitz DM, Eickholt C, Hofmann A, Langbein H, Brux M, Engelmann F, Goettsch C, Goettsch W, Augstein A, Bornstein SR, Strasser RH, Breier G, Siow RC, Morawietz H (2018)
Hypoxia upregulates NADPH oxidase 4-mediated hydrogen peroxide release by a HIF-independent mechanism in human endothelial cells
Second Joint Meeting between the German Society for Microcirculation and Vascular Biology, Dutch Endothelial Biology Society & Dutch Society for Microcirculation and Vascular Biology, November 21-13, 2018, Amsterdam, the Netherlands
Abstract book:12

Brunssen C, Giebe S, Hofmann A, Brux M, Hewitt K, Lowe F, Morawietz H (2018)
Impact of cigarette smoke, next generation tobacco and nicotine products on the cytotoxic, oxidative and pro-inflammatory status of THP-1 cells
Second Joint Meeting between the German Society for Microcirculation and Vascular Biology, Dutch Endothelial Biology Society & Dutch Society for Microcirculation and Vascular Biology, November 21-13, 2018, Amsterdam, the Netherlands
Abstract book:11

Almedawar MM, Brux M, Brunssen C, Morawietz H (2018)
Cigarette smoke impairs the anti-oxidative response by reducing heme levels and inducing Bach1
25^th Annual Meeting of the Society for Redox Biology and Medicine (SfRBM), November 14-17, 2018, Chicago, IL, USA
Free Radic. Biol. Med. 128 (Suppl 1):s21

Almedawar MM, Brux M, Brunssen C, Morawietz H (2018)
Cigarette smoke impairs the anti-oxidative response by reducing heme levels and inducing Bach1
Circulation 138 (Suppl. 1):A16728 (Su1247)

Langbein H, Shahid A, Hofmann A, Mittag J, Bornstein SR,Morawietz H, Brunßen C (2018)
Protective effects of exercise on vascular function are mediated by NADPH oxidase 4
Circulation 138 (Suppl. 1):A15590 (Mo1192)

Langbein H, Shahid A, Cimalla P, Schnabel C, Koch E, Morawietz H, Brunssen C (2018)
Optical coherence tomography as a novel method to measure endothelial dysfunction in mice in vivo
Europhysiology 2018, September 14-16, 2018, London, UK
Europhysiology 2018 abstract book:469P (PCB347)

Cybularz M, Langbein H, Zatschler B, Brunssen C, Deussen A, Matschke K,Morawietz H (2018)
Mineralocorticoid receptor antagonist therapy improves vascular function in patients with coronary artery disease
Eur. Heart J. 39 (Suppl 1):745 (P3606), ehy563.P3606, https://doi.org/10.1093/euheart/ehy563.P3606

Brunssen C, Arsov A, Poitz DM, Eickholt C, Hofmann A, Langbein H, Brux M, Engelmann F, Goettsch C, Goettsch W, Augstein A, Bornstein SR, Strasser RH, Breier G, Morawietz H (2018)
Hypoxia upregulates NADPH oxidase 4-mediated hydrogen peroxide release by a HIF-independent mechanism in human endothelial cells
Vascular Discovery: From Genes to Medicine, Scientific Sessions 2018 (Formerly ATVB|PVD Scientific Sessions), May 10-12, 2018, San Francisco, CA, Final Program:676

Brunssen C, Giebe S, Hofmann A, Brux M, Hewitt K, Lowe F, Morawietz H (2018)
Impact of cigarette smoke, next generation tobacco and nicotine products on the cytotoxic, oxidative and pro-inflammatory status of THP-1 cells
Vascular Discovery: From Genes to Medicine, Scientific Sessions 2018 (Formerly ATVB|PVD Scientific Sessions), May 10-12, 2018, San Francisco, CA, Final Program:241

Brunssen C, Giebe S, Hofmann A, Brux M, Hewitt K, Lowe F, Morawietz H (2018)
Impact of cigarette smoke, next generation tobacco and nicotine products on the cytotoxic, oxidative and pro-inflammatory status of THP-1 cells
Frontiers in CardioVascular Biology, April 20-22, 2018, Vienna, Austria
Cardiovasc. Res. 114 (Suppl 1):S133 (P545), https://doi.org/10.1093/cvr/cvy060.401

Langbein H, Cimalla P, Schnabel C, Hofmann A, Koch E, Morawietz H, Brunssen C (2018)
Optical coherence tomography as a novel method to measure endothelial dysfunction in mice in vivo
Frontiers in CardioVascular Biology, April 20-22, 2018, Vienna, Austria
Cardiovasc. Res. 114 (Suppl 1):S89 (P348), https://doi.org/10.1093/cvr/cvy060.261

Almedawar MM, Giebe S, Brux M, Brunssen C, Morawietz H (2018)
Cigarette smoke-induced BACH1 regulates the cross talk between NRF2 and AHR through inhibiting microRNA-125b
Frontiers in CardioVascular Biology, April 20-22, 2018, Vienna, Austria
Cardiovasc. Res. 114 (Suppl 1):S41 (P155), https://doi.org/10.1093/cvr/cvy060.116

O’Neill KM, Campbell DC, Edgar KS, Moez A, McLoughlin KJ, O’Neill CL, Dellett M, Hargey CJ, Abudalo RA, Gill EK, Doyle P, Toh T, Khoo J, McCrudden CM, Brunssen C, Morawietz H, Yoder MC, Stitt AW, Margariti A, Medina RJ, Grieve DJ (2018)
NADPH oxidase 4 is a major regulator of cord blood-derived endothelial colony-forming cells which promotes postischemic revascularisation
Heart 104 (Suppl 4): A3-A4 (Meeting abstract 8), DOI: 10.1136/heartjnl-2018-SCF.8

Willmes DM, Schumann T, Henke C, Kurzbach A, Luft F, Morawietz H, Helfand S, El-Armouche A, Mueller D, Bornstein SR, Tank J, Eisenhofer G, Daniels M, Jordan J, Birkenfeld A (2018)
The longevity gene mINDY (I’m Not Dead, Yet) affects blood pressure through sympathoadrenal mechanisms
J. Am. Coll. Cardiol. 71 (Suppl.):1813 (A1813), DOI: 10.1016/S0735-1097(18)32354-4
(Award as highest ranking abstract from Germany)

Cybularz M, Langbein H, Zatschler B, Brunßen C, Deussen A, Matschke K,Morawietz H (2018)
Mineralocorticoid receptor antagonist therapy improves vascular function in patients with coronary artery disease
Clin Res Cardiol 107 (Suppl 1):P1727, DOI 10.1007/s00392-018-1216-4

Langbein H, Brunßen C, Hofmann A, Shahid A, Mittag J,Morawietz H (2018)
NADPH oxidase 4 is essential for beneficial effects of endurance exercise on vascular function
Clin Res Cardiol 107 (Suppl 1):P1394, DOI 10.1007/s00392-018-1216-4

Willmes D, Lieske S, Hofmann A, da Costa-Gonzalves A, Schumann T, Henke C, Kurzbach A, Luft F, Helfand S, Morawietz H, El-Armouche A, Müller D, Eisenhofer G, Tank J, Jordan J, Birkenfeld A (2018)
Role of the Longevity Gene mINDY (I’m Not Dead, Yet) in Arterial Blood Pressure Regulation
Clin Res Cardiol 107 (Suppl 1):P1391, DOI 10.1007/s00392-018-1216-4

Brunßen C, Giebe S, Hofmann A, Brux M, Hewitt K, Lowe F, Morawietz H (2018)
Impact of cigarette smoke, next generation tobacco and nicotine products on the cytotoxic, oxidative and pro-inflammatory status of THP-1 cells
Clin Res Cardiol 107 (Suppl 1):P775, DOI 10.1007/s00392-018-1216-4

Publications 2017

Muller G, Meissner S, Walther J, Koch E, Morawietz H (2017)
In vivo imaging of murine vasodynamics analyzing different mouse strains by Optical Coherence Tomography
Atheroscler. Suppl. 30:311-318. doi: 10.1016/j.atherosclerosissup.2017.05.023 [https://www.ncbi.nlm.nih.gov/pubmed/29096856]

Parshyna I, Lehmann S, Grahl K, Pahlke C, Frenzel A, Weidlich H, Morawietz H (2017)
Impact of omega-3 fatty acids on expression of angiogenic cytokines and angiogenesis by adipose-derived stem cells
Atheroscler. Suppl. 30:303-310. doi: 10.1016/j.atherosclerosissup.2017.05.040 [https://www.ncbi.nlm.nih.gov/pubmed/29096855]

Hofmann A, Brunssen C, Poitz DM, Langbein H, Strasser RH, Henle T, Ravens U, Morawietz H (2017)
Lectin-like oxidized low-density lipoprotein receptor-1 promotes endothelial dysfunction in LDL receptor knockout background
Atheroscler. Suppl. 30:294-302. doi: 10.1016/j.atherosclerosissup.2017.05.020 [https://www.ncbi.nlm.nih.gov/pubmed/29096854]

Cybularz M, Langbein H, Zatschler B, Brunssen C, Deussen A, Matschke K, Morawietz H (2017)
Endothelial function and gene expression in perivascular adipose tissue from internal mammary arteries of obese patients with coronary artery disease
Atheroscler. Suppl. 30:149-158. doi: 10.1016/j.atherosclerosissup.2017.05.042 [https://www.ncbi.nlm.nih.gov/pubmed/29096831]

Engel B, Müller G, Roch B, Schröder HE, Aringer M, Bornstein SR, Morawietz H (2017)
Serum of patients with antiphospholipid syndrome induces adhesion molecules in endothelial cells
Atheroscler. Suppl. 30:141-148. doi: 10.1016/j.atherosclerosissup.2017.05.039 [https://www.ncbi.nlm.nih.gov/pubmed/29096830]

Brunssen C, Hofmann A,Peitzsch M, Frenzel A, Ziegler CG, Brown NF, Weldon SM, Eisenhofer G, Willenberg HS, Bornstein SR, Morawietz H (2017)
Impact of aldosterone synthase inhibitor FAD286 on steroid hormone profile in human adrenocortical cells
Horm. Metab. Res. 49(9):701-706. doi: 10.1055/s-0043-113829 [https://www.ncbi.nlm.nih.gov/pubmed/28759940]

Giebe S, Cockcroft N, Hewitt K, Brux B, Hofmann A, Morawietz H*, Brunssen C* (2017)
Cigarette smoke extract counteracts atheroprotective effects of high laminar flow on endothelial function
Redox Biol. 12:776-786. doi: 10.1016/j.redox.2017.04.008 [https://www.ncbi.nlm.nih.gov/pubmed/28432984]

Hofmann A, Brunssen C, Peitzsch M, Balyura M, Mittag J, Frenzel A, Jannasch A, Brown NF, Weldon SM, Gueneva-Boucheva KK, Eisenhofer G, Bornstein SR, Morawietz H (2017)
The aldosterone synthase inhibitor FAD286 is suitable for lowering aldosterone levels in ZDF rats but not in db/db mice
Horm. Metab. Res. 49(6):466-471. doi: 10.1055/s-0043-101821 [https://www.ncbi.nlm.nih.gov/pubmed/28427090]

Al-Gburi S, Deussen A, Zatschler B, Weber S, Künzel S, El-Armouche A, Lorenz K, Cybularz M, Morawietz H, Kopaliani I (2017)
Sex-difference in expression and function of beta-adrenoceptors in macrovessels: role of the endothelium
Basic Res Cardiol. 112(3):29 (1-16). doi: 10.1007/s00395-017-0617-2 [https://www.ncbi.nlm.nih.gov/pubmed/28389717]

Brunssen C, Giebe S, Hofmann A, Brux M, Morawietz H (2017)
Evaluation of cytotoxic, oxidative and pro-inflammatory effects of aqueous cigarette smoke extract on human monocytes: a potential model system for assessment of next generation tobacco and nicotine products
Applied In Vitro Toxicology 3(1):121-130. doi:10.1089/aivt.2016.0037 [https://www.liebertpub.com/doi/10.1089/aivt.2016.0037]

Schwafertz C, Schinner S, Kühn MC, Haase M, Asmus A, Mülders-Opgenoorth B, Ansurudeen I, Hornsby PJ, Morawietz H, Oetjen E, Schott M, Willenberg HS (2017)
Endothelial cells regulate β-catenin activity in adrenocortical cells via secretion of basic fibroblast growth factor
Mol. Cell. Endocrinol. 441:108-115. doi: 10.1016/j.mce.2016.11.015 [https://www.ncbi.nlm.nih.gov/pubmed/27889473]

Hofmann A, Peitzsch M, Brunssen C, Mittag J, Jannasch A, Frenzel A, Brown NF, Weldon SM, Eisenhofer G, Bornstein SR, Morawietz H (2017)
Elevated steroid hormone production in the db/db mouse model of obesity and type 2 diabetes
Horm. Metab. Res. 49(1):43–49. doi: 10.1055/s-0042-116157 [https://www.ncbi.nlm.nih.gov/pubmed/27813053]

Abstracts 2017

Fink B, Brunssen C, Morawietz H, Rabovsky A (2017)
Multifunctional supplement is that the key to modulate redox signaling in metabolic syndrome volunteers: cellular metabolic index
Free Radic. Biol. Med. 112 (Suppl 1):S150 (216), DOI: 10.1016/j.freeradbiomed.2017.10.229

CybularzM, LangbeinH, ZatschlerB, BrunssenC, DeussenA, MatschkeK, Morawietz H (2017)
Mineralocorticoid receptor antagonist therapy improves vascular function in patients with coronary artery disease
Circulation 136 (Suppl. 1): A20004

Brunssen C, Rissler J, Langbein H, Hofmann A, Deussen A, Peitzsch M, Cimalla P, Koch E, Eisenhofer G, Sawamura T, Morawietz H (2017)
Eplerenone and vascular function in LOX-1 overexpressing mice on high-fat diet
Circulation 136 (Suppl. 1): A16549

Morawietz H, Catar RA, Goettsch C, Taye A, Hofmann A, Brunssen C, Muller G, Lehmann S, Schubert U, Ludwig B, Ziegler CG, Bornstein SR, Krug AW, Walther T (2017)
Oxidized LDL, angiotensin II and oxidative stress
39^th Annual Meeting of the German Society for Microcirculation and Vascular Biology (GfMVB) - Peaks in Vascular Biology, Grainau/Garmisch-Partenkirchen, Germany, Abstract book:0024

Almedawar MM, Giebe S, Brux M, Brunssen C, Morawietz H (2017)
Cross-talk between the nuclear factor endothelial 2 like 2 and the aryl hydrocarbon receptor via microRNA-125b in the response of endothelial cells to cigarette smoke exposure
39^th Annual Meeting of the German Society for Microcirculation and Vascular Biology (GfMVB) - Peaks in Vascular Biology, Grainau/Garmisch-Partenkirchen, Germany, Abstract book:0023

BrunssenC, GiebeS, HofmannA,BruxM,HewittK, LoweF, Morawietz H (2017)
Impact of cigarette smoke, next generation tobacco and nicotine products on the cytotoxic, oxidative and pro-inflammatory status of THP-1 cells
Eurotox - 53^rd Congress of the European Societies of Toxicology 2017, Bratislava, Congress Program:87 (ID 646 - P-04-09-02)
Toxicol. Lett. 280 (Suppl 1):S160,
http://dx.doi.org/10.1016/j.toxlet.2017.07.449

Catar RA, Goettsch C, Taye A, Hofmann A, Brunssen C, Muller G, Shahid A, Lehmann S, Schubert U, Ludwig B, Ziegler CG, Bornstein SR, Krug AW, Walther T, Morawietz H (2017)
Interaction between oxidized LDL, angiotensin II and oxidative stress
European Society of Cardiology Congress, August 26-30, 2017, Barcelona, Spain
Eur. Heart J. 38 (Suppl 1):1343-1344 (P6286), https://doi.org/10.1093/eurheartj/ehx493.P6286

Almedawar MM, Giebe S, Brux M, Brunssen C, Morawietz H (2017)
Regulation of exosomal and cellular miRNA-125b within the anti-oxidative response to cigarette smoking
European Society of Cardiology Congress, August 26-30, 2017, Barcelona, Spain
Eur. Heart J. 38 (Suppl 1):732 (P3481), https://doi.org/10.1093/eurheartj/ehx504.P3481

Almedawar MM, Giebe S, Brux M, Brunssen C, Morawietz H (2017)
Inhibition of miRNA-125b within the anti-oxidative response to cigarette smoking
11^th CRTD Summer Conference on Regenerative Medicine 2017, Dresden, Book of Abstracts:40 (Poster session 2/147)

Morawietz H, Catar RA, Goettsch C, Taye A, Hofmann A, Brunssen C (2017)
Oxidized LDL, angiotensin II and oxidative stress
2^nd Joint Meeting of the European Society for Microcirculation (ESM) and European Vascular Biology Organization (EVBO), May 29 - June 1, 2017, Geneva, Abstracts
J. Vasc. Res. 54 (Suppl. 1):47 (7C-01)

Almedawar MM, Giebe S, Brux M, Brunssen C, Morawietz H (2017)
Inhibition of miRNA-125b within the anti-oxidative response to cigarette smoking
2^nd Joint Meeting of the European Society for Microcirculation (ESM) and European Vascular Biology Organization (EVBO), May 29 - June 1, 2017, Geneva, Abstracts
J. Vasc. Res. 54 (Suppl. 1):42 (6A-03)

Rodionov RN, Burdin D, Brilloff S, Todorov V, Jarzebska N, Martens-Lobenhoffer J, Hofmann A, Morawietz H, Hilgers K, Cordasic N, Jacobi J, Maas R, Chen Y, Bode-Böger SM, Hugo CP, Hohenstein B, Weiss N (2017)
Transgenic overexpression of alanine-glyoxylate aminotransferase 2 in mice lowers asymmetric dimethylarginine and improves vasomotor function
Arterioscler. Thromb. Vasc. Biol. 37 (1):185

Cybularz M, Langbein H, Zatschler B, Brunßen C, Deussen A, Matschke K, Morawietz H (2017)
Endothelial function and gene expression in perivascular adipose tissue from internal mammary arteries of obese patients with coronary artery disease
Clin Res Cardiol 106 (Suppl 1):P1143, DOI 10.1007/s00392-017-1105-2
83. Jahrestagung der Deutschen Gesellschaft für Kardiologie- Herz- und Kreislaufforschung e.V., Mannheim, 19.-22.04.2017
Nominiertes Poster Posterbereich Therapie und Verlauf bei koronaren Herzkrankheit
83^rd Annual Meeting of the German Cardiac Society, Mannheim, April 19-22, 2017
Poster Award Poster Session Therapy and Progression of Coronary Heart Disease

Parshyna I, Lehmann S, Grahl K, Pahlke C, Frenzel A, Weidlich H, Morawietz H (2017)
Impact of omega-3 fatty acids on expression of angiogenic cytokines and angiogenesis by adipose-derived stem cells
Clin Res Cardiol 106 (Suppl 1):P1078, DOI 10.1007/s00392-017-1105-2

Kopaliani I, Al-Gburi S, Zatschler B, Weber S, El-Armouche A, Lorenz K, Cybularz M, Morawietz H, Deussen A (2017)
Sex-specific expression of β-adrenoceptors in macrovessels
Clin Res Cardiol 106 (Suppl 1):V42, DOI 10.1007/s00392-017-1105-2

Kopaliani I, Al-Gburi S, Zatschler B, Weber S, El-Armouche A, Lorenz K, Cybularz M, Morawietz H, Deussen A (2017)
Sex-specific difference in expression and function of beta-adrenoceptors in macrovessels: role of the endothelium
Acta Physiol. (Oxf.) 219 (Suppl 711):142-143 (B04-12)

Cybularz M, Langbein H, Zatschler B, Brunssen C, Deussen A, Matschke K, Morawietz H (2017)
Endothelial function and gene expression in perivascular adipose tissue from internal mammary arteries of obese patients with coronary artery disease
96^th Annual Meeting of the German Physiological Society 2017, Greifswald
Acta Physiol. (Oxf.) 219 (Suppl 711):111 (A07-11)

Almedawar MM, Giebe S, Brux M, Morawietz H, Brunssen C (2017)
Regulation of exosomal and cellular miRNA-125b within the anti-oxidative response to cigarette smoking
96^th Annual Meeting of the German Physiological Society 2017, Greifswald
Acta Physiol. (Oxf.) 219 (Suppl 711):109 (A07-7)

Engel B, Müller G, Roch B, Schröder HE, Aringer M, Bornstein SR, Morawietz H (2017)
Serum of patients with antiphospholipid syndrome induces adhesion molecules in endothelial cells
96^th Annual Meeting of the German Physiological Society 2017, Greifswald
Acta Physiol. (Oxf.) 219 (Suppl 711):108 (A07-4)

Brunssen C, Peitzsch M, Ziegler CG, Frenzel A, Brown NF, Weldon SM, Eisenhofer G, Willenberg HS, Bornstein SR, Morawietz H, Hofmann A (2017)
Impact of aldosterone synthase inhibitor FAD286 on steroid hormone profile in human adrenocortical cells
96^th Annual Meeting of the German Physiological Society 2017, Greifswald
Acta Physiol. (Oxf.) 219 (Suppl 711):98-99 (A05-8)

Giebe S, Brux M, Cockcroft N, Hewitt K, Morawietz H, Brunssen C (2017)
Cigarette smoke extract abrogates atheroprotective effects of high laminar flow on endothelial function
7^th Student Retreat, International PhD Program “Homeostatic and regulatory functions of endothelium”, January 20, February 10, 2017, Dresden, Abstract book:20

Almedawar MM, Giebe S, Brux M, Brunssen C Morawietz H (2017)
Regulation of exosomal and cellular miRNA-125b within the anti-oxidative response to cigarette smoking
7^th Student Retreat, International PhD Program “Homeostatic and regulatory functions of endothelium”, January 20, February 10, 2017, Dresden, Abstract book:7

Publications 2016

Brandt M, Garlapati V, Oelze M, Sotiriou E, Knorr M, Kröller-Schön S, Kossmann S, Schönfelder T, Morawietz H, Schulz E, Schultheiss HP, Daiber A, Münzel T, Wenzel P (2016)
NOX2 amplifies acetaldehyde-mediated cardiomyocyte mitochondrial dysfunction in alcoholic cardiomyopathy
Sci. Rep.6:32554. doi: 10.1038/srep32554 [https://www.ncbi.nlm.nih.gov/pubmed/27624556]

Hofmann A, Brunssen C, Peitzsch M, Martin M, Mittag J, Jannasch A, Engelmann F, Brown NF, Weldon SM, Huber J, Streicher R, Deussen A, Eisenhofer G, Bornstein SR, Morawietz H (2016)
Aldosterone synthase inhibition improves glucose tolerance in Zucker Diabetic Fatty (ZDF) rats
Endocrinology 157:3844-3855. doi: 10.1210/en.2016-1358 [https://www.ncbi.nlm.nih.gov/pubmed/27526033]

Hofmann A, Sawamura T, Morawietz H (2016)
LOX-1 and immunity
In: “C-Type Lectin Receptors in Immunity”. Ed. by S. Yamasaki, Springer Nature, Japan, 151-163, DOI: 10.1007/978-4-431-56015-9_10

Roehlecke C, Valtink M, Frenzel A, Goetze D, Knels L, Morawietz H, Funk RHW (2016)
Stress responses of human retinal pigment epithelial cells to glyoxal
Graefes Arch. Clin. Exp. Ophthalmol. 254:2361-2372. doi:10.1007/s00417-016-3463-2 [https://www.ncbi.nlm.nih.gov/pubmed/27520463]

Otto S, Deussen A, Zatschler B, Müller B, Neisser A, Barth K, Morawietz H, Kopaliani I (2016)
A novel role of endothelium in activation of latent pro-membrane type 1 MMP and pro-MMP-2 in rat aorta
Cardiovasc. Res. 109:409-418. doi: 10.1093/cvr/cvv256 [https://www.ncbi.nlm.nih.gov/pubmed/26598508]

Morawietz H (2016)
Herz-Kreislauf-Schutz mit Sauerstoffradikalen
Cardio News 19 (1-2):37

Langbein H, Brunssen C, Hofmann A, Cimalla P, Brux M, Bornstein SR, Deussen A, Koch E, Morawietz H (2016)
NADPH oxidase 4 protects against development of endothelial dysfunction and atherosclerosis in LDL receptor deficient mice
Eur. Heart J. 37:1753-1761. doi: 10.1093/eurheartj/ehv564 [https://www.ncbi.nlm.nih.gov/pubmed/26578199]

Abstracts 2016

Almedawar MM, Giebe S, Brux M, Brunssen C Morawietz H (2016)
Role of miRNA-125b in the modulation of endothelial anti-oxidative response to cigarette smoking
Society for Redox Biology and Medicine/Society for Free Radical Research Meeting, November 16-19, 2016, San Francisco, CA, USA
Free Radic. Biol. Med. 100 (Suppl 1):S136 (313)
Poster Award

Rodionov R, Burdin D, Brilloff S, Todorov V, Jarzebska N, Martens-Lobenhoffer J, Hofmann A, Morawietz H, Demyanov A, Hilgers K, Cordasic N, Jacobi J, Maas R, Chen Y, Bode-Böger SM, Hugo CP, Hohenstein B, Weiss N (2016)
Transgenic overexpression of alanine-glyoxylate aminotransferase 2 in mice lowers asymmetric dimethylarginine and improves vasomotor function
Circulation 134 (Suppl. 1): A19529
Catar RA, Goettsch C, Taye A, Hofmann A, Brunssen C, Muller G, Lehmann S, Schubert U, Ludwig B, Ziegler CG, Bornstein SR, Krug AW, Walther T, Morawietz H (2016)
Interaction between oxidized LDL, angiotensin II and oxidative stress
Circulation 134 (Suppl. 1): A16538

Langbein H, Cimalla P, Schnabel C, Hofmann A, Koch E, Morawietz H, Brunssen C (2016)
Optical Coherence Tomography as a novel method to measure endothelial dysfunction in mice in vivo
Joint International Meeting of the German Society for Microcirculation and Vascular Biology (GfMVB) and the DFG-SFB 834 Endothelial Signalling and Vascular Repair - Perspectives in Vascular Biology 2016, Frankfurt, Germany, Abstract book:P-119

Morawietz H, Giebe S, Cockcroft N, Hewitt K, Brux M, Brunssen C (2016)
Cigarette smoke extract abrogates atheroprotective effects of high laminar flow on endothelial function
European Society of Cardiology Congress, August 27-31, 2016, Rome, Italy
Eur. Heart J. 37 (Suppl 1):554 (P2742)

Morawietz H, Giebe S, Cockcroft N, Hewitt K, Brux M, Brunssen C (2016)
Cigarette smoke extract abrogates atheroprotective effects of high laminar flow on endothelial function
Frontiers in CardioVascular Biology, July 08-10, 2016, Florence, Italy
Cardiovasc. Res. 111 (Suppl 1):S104 (587)

Langbein H, Hofmann A, Morawietz H, Brunssen C (2016)
Key role of NADPH oxidase 4 in a model of reversible endothelial dysfunction
10^th CRTD Summer Conference on Regenerative Medicine 2016, Dresden:ID81

Almedawar MM, Giebe S, Brux M, Brunssen C Morawietz H, (2016)
Role of miRNA-125b in the modulation of endothelial anti-oxidative response to cigarette smoking
10^th CRTD Summer Conference on Regenerative Medicine 2016, Dresden:ID77

Cybularz M, Langbein H, Zatschler B, Brunssen C, Deussen A, Matschke K, Morawietz H (2016)
Endothelial function and gene expression in perivascular adipose tissue from internal mammary arteries of obese patients with coronary artery disease
10^th CRTD Summer Conference on Regenerative Medicine 2016, Dresden:ID73

Rojo Arias JE, Montecino Garrido H, Economopoulou M, Morawietz H, Funk RHW, Jászai J (2016)
Aflibercept counteracts pathologic vaso-proliferation and triggers a tip cell-driven regeneration of the retinal vasculature after hypoxic damage in mice
10^th CRTD Summer Conference on Regenerative Medicine 2016, Dresden:ID71

Langbein H, Brunssen C, Hofmann A, Cimalla P, Brux M, Bornstein SR, Deussen A, Koch E, Morawietz H (2016)
NADPH oxidase 4 protects against development of endothelial dysfunction and atherosclerosis in LDL receptor deficient mice
Clin Res Cardiol 105 (Suppl 1):P1749, DOI 10.1007/s00392-016-0967-z

Giebe S, Cockcroft N, Hewitt K, Brux M, Morawietz H, Brunssen C (2016)
Cigarette smoke extract abrogates atheroprotective effects of high laminar flow on endothelial function
Clin Res Cardiol 105 (Suppl 1):P1069, DOI 10.1007/s00392-016-0967-z

Cybularz M, Langbein H, Zatschler B, Brunssen C, Deussen A, Matschke K, Morawietz H (2016)
Endothelial function and gene expression in perivascular adipose tissue from internal mammary arteries of obese patients with coronary artery disease
4^th Dresden International Symposium on Therapeutic Apheresis/1^st Congress of the European Group - International Society for Apheresis, March 17-19, 2016, Dresden, Program:31 (P09)

Parshyna I, Lehmann S, Grahl K, Kühn C, Frenzel A, Weidlich H, Morawietz H (2016)
Adipose-derived stem cells, omega-3 fatty acids and angiogenesis
4^th Dresden International Symposium on Therapeutic Apheresis/1^st Congress of the European Group - International Society for Apheresis, March 17-19, 2016, Dresden, Program:31 (P06)

Müller G, Meissner S, Walther J, Koch E, Morawietz H (2016)
In vivo imaging of murine vasodynamics analyzing different mouse strains by Optical Coherence Tomography
4^th Dresden International Symposium on Therapeutic Apheresis/1^st Congress of the European Group - International Society for Apheresis, March 17-19, 2016, Dresden, Program:31 (P05)

Engel B, Müller G, Roch B, Schröder HE, Aringer M, Bornstein SR, Morawietz H (2016)
Serum of patients with antiphospholipid syndrome induces adhesion molecules in endothelial cells
4^th Dresden International Symposium on Therapeutic Apheresis/1^st Congress of the European Group - International Society for Apheresis, March 17-19, 2016, Dresden, Program:30 (P04)

Hofmann A, Brunssen C, Poitz DM, Strasser RH, Henle T, Ravens U, Morawietz H (2016)
Lectin-like oxidized low-density lipoprotein receptor-1 promotes inflammation in adipose tissue and endothelial dysfunction
4^th Dresden International Symposium on Therapeutic Apheresis/1^st Congress of the European Group - International Society for Apheresis, March 17-19, 2016, Dresden, Program:22

Langbein H, Hofmann A, Morawietz H, Brunssen C (2016)
Key role of NADPH oxidase 4 in a model of reversible endothelial dysfunction
95^th Annual Meeting of the German Physiological Society 2016, Lübeck
Acta Physiol. (Oxf.) 216 (Suppl 707):153-154 (P11-12)

Cybularz M, Langbein H, Zatschler B, Brunssen C, Deussen A, Matschke K, Morawietz H (2016)
Improved vascular function after mineralocorticoid receptor antagonist therapy in patients with coronary artery disease
95^th Annual Meeting of the German Physiological Society 2016, Lübeck
Acta Physiol. (Oxf.) 216 (Suppl 707):150 (P11-05)

Giebe S, Cockcroft N, Hewitt K, Brux M, Morawietz H, Brunssen C (2016)
Cigarette smoke extract abrogates atheroprotective effects of high laminar flow on endothelial function
95^th Annual Meeting of the German Physiological Society 2016, Lübeck
Acta Physiol. (Oxf.) 216 (Suppl 707):149-150 (P11-03)

Engelmann F, Brunssen C, Morawietz H (2016)
Transcriptional regulation of NADPH Oxidase 4 (NOX4) - Implication of JUN- and NFAT like elements
95^th Annual Meeting of the German Physiological Society 2016, Lübeck
Acta Physiol. (Oxf.) 216 (Suppl 707):141 (P09-12)

Publications 2015

Poitz DM, Ende G, Stütz B, Augstein A, Friedrichs J, Brunssen C, Werner C, Strasser RH, Jellinghaus S (2015)
EphrinB2/EphA4-mediated activation of endothelial cells increases monocyte adhesion
Mol. Immunol. 68(2 Pt C):648-56. doi: 10.1016/j.molimm.2015.10.009 [https://pubmed.ncbi.nlm.nih.gov/26552760/]

Kotomin I, Valtink M, Hofmann K, Frenzel A, Morawietz H, Werner C, Funk RHW, Engelmann K (2015)
Sutureless fixation of amniotic membrane for therapy of ocular surface disorders
PLoS One 10(5):e0125035. doi: 10.1371/journal.pone.0125035 [https://www.ncbi.nlm.nih.gov/pubmed/25955359]

Langbein H, Hofmann A, Brunssen C, Goettsch W, Morawietz H (2015)
Impact of high-fat diet and voluntary running on body weight and endothelial function in LDL receptor knockout mice
Atheroscler. Suppl. 18:59-66. http://dx.doi.org/10.1016/j.atherosclerosissup.2015.02.010 [https://www.ncbi.nlm.nih.gov/pubmed/25936306]

Catar RA, Muller G, Brandt A, Langbein H, Brunssen C, Goettsch C, Frenzel A, Hofmann A, Goettsch W, Steinbronn N, Strasser RH, Schubert U, Ludwig B, Bornstein SR, Morawietz H (2015)
Increased gene expression of the cardiac endothelin system in obese mice
Horm. Metab. Res. 47:509-515. (cover picture) DOI http://dx.doi.org/10.1055/s-0034-1387761 [https://www.ncbi.nlm.nih.gov/pubmed/25181417]

Abstracts 2015

Schubert U, Morawietz H, Bornstein SR, Ludwig B (2015)
The intra-adrenal islet transplantation model. Convergence of pancreatic islets with endocrine “helper cells”
Transplantation 99 (Suppl 2):S121

Schubert U, Morawietz H, Bornstein SR, Ludwig B (2015)
The intra-adrenal islet transplantation model. Convergence of pancreatic islets with endocrine “helper cells”
Xenotransplantation 22 (Suppl 1):S74-S75 (523)

Rodionov RN, Burdin D, Brilloff S, Todorov V, Jarzebska N, Martens-Lobenhoffer J, Demyanov AV, Hilgers K, Cordasic N, Jacobi J, Maas R, Hofmann A, Morawietz H, Bode-Böger SM, Hugo CP, Hohenstein B, Weiss N (2015)
Transgenic overexpression of alanine-glyoxylate aminotransferase 2 in mice lowers asymmetric dimethylarginine and improves endothelial function
Circulation 132 (Suppl. 3):A17603

Langbein H, Brunssen C, Hofmann A, Cimalla P, Bornstein SR, Koch E, Morawietz H (2015)
NADPH oxidase 4 protects against development of endothelial dysfunction and atherosclerosis in LDL receptor deficient mice
Circulation 132 (Suppl. 3):A15112

Almedawar MM, Giebe S, Brux M, Cockcroft N, Hewitt K, Brunssen C Morawietz H, (2015)
In vitro exposure of endothelial cells to cigarette smoke extract and shear stress regulate the expression of anti-oxidative transcription factors
6^th Student Retreat, International PhD Program “Homeostatic and regulatory functions of endothelium”, November 6-7, 2015, Dresden, Abstract book:22

Giebe S, Cockcroft N, Hewitt K, Brux M, Morawietz H, Brunssen C (2015)
Cigarette smoke extract abrogates atheroprotective effects of high laminar flow on endothelial function
6^th Student Retreat, International PhD Program “Homeostatic and regulatory functions of endothelium”, November 6-7, 2015, Dresden, Abstract book:13

Jászai J, Rojo Arias JE, von Herrmanni F, Kappert V, Economopoulou M, Morawietz H, Chavakis T, Funk RHW (2015)
Counteracting microvascular modifications in a murine oxygen-induced vaso-proliferative retinopathy model. Anatomische Gesellschaft, 110^th Annual Meeting/31. Arbeitstagung, September 23-25, Würzburg, Germany, Abstracts:Poster 93

Engelmann F, Brunssen C, Brux M, Morawietz H (2015)
Analysis of 5´ regulatory sequences of the human NADPH oxidase 4 gene in endothelial cells
9^th CRTD Summer Conference on Regenerative Medicine 2015, Dresden:ID100

Giebe S, Cockcroft N, Hewitt K, Brux M, Morawietz H, Brunssen C (2015)
Cigarette smoke extract abrogates atheroprotective effects of high laminar flow on endothelial function
9^th CRTD Summer Conference on Regenerative Medicine 2015, Dresden:ID52

Hofmann A, Langbein H, Brunssen C, Morawietz H (2015)
Impact of high-fat diet and voluntary running on body weight and endothelial function in LDL receptor knockout mice
9^th CRTD Summer Conference on Regenerative Medicine 2015, Dresden:ID49

Langbein H, Hofmann A, Brunssen C, Cimalla P, Koch E, Morawietz H (2015)
NADPH oxidase 4 protects against development of endothelial dysfunction and atherosclerosis in LDL receptor deficient mice
9^th CRTD Summer Conference on Regenerative Medicine 2015, Dresden:ID33

Eickholt C, Brunssen C, Brux M, Goettsch C, Langbein H, Goettsch W, Morawietz H (2015)
Maintenance of endothelial NO release after inhibition of NADPH oxidase 4
Joint 28^th European Society for Microcirculation and 8^th European Vascular Biology Organization Meeting, June 3-6, 2015, Pisa, Abstracts
J Vasc Res 52(suppl 1):44-45

Brunssen C, Rissler J, Langbein H, Hofmann A, Frenzel A, Deussen A, Peitzsch M, Cimalla P, Koch E, Eisenhofer G, Sawamura T, Morawietz H (2015)
Impact of eplerenone on vascular function in LOX-1 overexpressing mice on high-fat diet
Arteriosclerosis, Thrombosis, and Vascular Biology 2015 Scientific Sessions, May 7-9, 2015, San Francisco, CA, Final Program and Abstracts:183-184
Arterioscler. Thromb. Vasc. Biol. 35 (Suppl 1):A543

Rodionov RN, Burdin DV, Todorov V, Brilloff S, Jarzebska N, Martens-Lobenhoffer J, Hofmann A, Morawietz H, Demyanov AV, Maas R, Bode-Böger SM, Hugo CP, Hohenstein B, Weiss N (2015)
Transgenic overexpression of alanine-glyoxylate aminotransferase 2 lowers tissue levels of asymmetric dimethylarginine and improves endothelial function in mouse aorta
Arteriosclerosis, Thrombosis, and Vascular Biology 2015 Scientific Sessions, May 7-9, 2015, San Francisco, CA, Final Program and Abstracts:133
Arterioscler. Thromb. Vasc. Biol. 35 (Suppl 1):A373

Brunssen C, Eickholt C, Langbein H, Brux M, Goettsch C, Goettsch W, Morawietz H (2015)
Neuronal nitric oxide synthase maintains endothelial NO release after inhibition of NADPH oxidase 4
Arteriosclerosis, Thrombosis, and Vascular Biology 2015 Scientific Sessions, May 7-9, 2015, San Francisco, CA, Final Program and Abstracts:88
Arterioscler. Thromb. Vasc. Biol. 35 (Suppl 1):A226

Giebe S, Cockcroft N, Hewitt K, Brux M, Morawietz H, Brunssen C (2015)
Cigarette smoke extract abrogates atheroprotective effects of high laminar flow on endothelial function
The 10^th International Symposium on Biomechanics in Vascular Biology and Cardiovascular Disease, 23-24^th April 2015, Rotterdam, The Netherlands, Abstract book:48

Giebe S, Brunssen C, Brux M, Cockcroft N, Hewitt K, Morawietz H (2015)
Local hemodynamic forces and aqueous cigarette smoke extract affect development of endothelial dysfunction
Clin Res Cardiol 104 (Suppl 1):V1606

Eickholt C, Brunssen C, Brux M, Goettsch C, Langbein H, Goettsch W, Morawietz H (2015)
Maintenance of endothelial NO release after inhibition of NADPH oxidase 4
Clin Res Cardiol 104 (Suppl 1):P763

Langbein H, Hofmann A, Brunssen C, Goettsch W, Morawietz H (2015)
Impact of high-fat diet and voluntary running on body weight and endothelial function in LDL receptor knockout mice
Clin. Res. Cardiol. 104 (Suppl 1):V538

Brunssen C, Eickholt C, Langbein H, Brux M, Hofmann A, Goettsch C, Goettsch W, Morawietz H (2015)
Maintenance of endothelial NO release after inhibition of NADPH oxidase 4
94^th Annual Meeting Deutsche Physiologische Gesellschaft 2015, Magdeburg
Acta Physiol. (Oxf.) 213 (Suppl 699):177 (P260)

Catar RA, Muller G, Brandt A, Langbein H, Brunssen C, Goettsch C, Frenzel A, Hofmann A, Goettsch W, Steinbronn N, Strasser RH, Schubert U, Ludwig B, Bornstein SR, Morawietz H (2015)
Increased gene expression of the cardiac endothelin system in obese mice
94^th Annual Meeting Deutsche Physiologische Gesellschaft 2015, Magdeburg
Acta Physiol. (Oxf.) 213 (Suppl 699):117-118 (P123)

Otto S, Kopaliani I, Zatschler B, Barth K, Kasper M, Morawietz H, Deussen A (2015)
A novel role of the endothelium in activation of latent pro-membrane type 1 matrix metalloproteinase (pro-MT1MMP) and pro-matrix metalloproteinase 2 (pro-MMP2) in rat aorta
94^th Annual Meeting Deutsche Physiologische Gesellschaft 2015, Magdeburg
Acta Physiol. (Oxf.) 213 (Suppl 699):51 (OS4-07)

Publications 2014

Morawietz H, Bornstein SR (2014)
Spironolactone for heart failure with preserved ejection fraction
N. Engl. J. Med. 371(2):181; doi: 10.1056/NEJMc1405715 [https://www.ncbi.nlm.nih.gov/pubmed/25006730]

Ende G, Poitz DM, Wiedemann E, Augstein A, Friedrichs J, Giebe S, Weinert S, Werner C, Strasser RH, Jellinghaus S (2014)
TNF-α-mediated adhesion of monocytes to endothelial cells-The role of ephrinA1
J. Mol. Cell. Cardiol. 77:125-35; doi: 10.1016/j.yjmcc.2014.10.010 [https://pubmed.ncbi.nlm.nih.gov/25451169/]

Abstracts 2014

Giebe S, Brunssen C, Brux M, Cockcroft N, Hewitt K, Morawietz H (2014)
Local hemodynamic forces and aqueous cigarette smoke extract affect development of endothelial dysfunction
5^th Student Retreat, International PhD Program “Homeostatic and regulatory functions of endothelium”, November 28-29, 2014, Dresden, Abstract book:24

Eickholt C, Brunssen C, Langbein H, Brux M, Hofmann A, Goettsch C, Goettsch W, Morawietz H (2014)
Maintenance of endothelial NO release after inhibition of NADPH oxidase 4
5^th Student Retreat, International PhD Program “Homeostatic and regulatory functions of endothelium”, November 28-29, 2014, Dresden, Abstract book:23

Langbein H, Brunssen C, Hofmann A, Goettsch W, Cimalla P, Koch E, Morawietz H (2014)
NADPH oxidase 4 and endothelial dysfunction
5^th Student Retreat, International PhD Program “Homeostatic and regulatory functions of endothelium”, November 28-29, 2014, Dresden, Abstract book:19

Eickholt C, Brunssen C, Langbein H, Brux M, Hofmann A, Goettsch C, Goettsch W, Morawietz H (2014)
Maintenance of endothelial NO release after inhibition of NADPH oxidase 4
Circulation 130 (Suppl.):A 15396

Schubert U, Morawietz H, Bornstein SR, Ludwig B (2014)
The adrenal gland and pancreatic islets: a beneficial endocrine alliance?
Transpl. Int. 27 (Suppl 3):31 (P023)

Eickholt C, Brunssen C, Langbein H, Brux M, Hofmann A, Goettsch C, Goettsch W, Morawietz H (2014)
Maintenance of endothelial NO release after inhibition of NADPH oxidase 4
3^rd Joint Meeting of the German Society of Microcirculation and Vascular Biology (GfMVB) and the Swiss Society for Microcirculation and Vascular Research (SSMVR), Münster, Germany, Programme - Abstracts:37 (ID 25)

Giebe S, Brunssen C, Brux M, Cockcroft N, Hewitt K, Morawietz H (2014)
Local hemodynamic forces and aqueous cigarette smoke extract affect development of endothelial dysfunction
3^rd Joint Meeting of the German Society of Microcirculation and Vascular Biology (GfMVB) and the Swiss Society for Microcirculation and Vascular Research (SSMVR), Münster, Germany, Programme - Abstracts:36 (ID 24)

Frenzel A, Mieting A, Goettsch W, Valtink M, Roehlecke C, Funk RHW, Becker KA, Engelmann K, Morawietz H (2014)
VEGF-A expression under prodiabetic conditions in human retinal and endothelial cells and the vitreous fluid of patients with type 2 diabetes
3^rd Joint Meeting of the German Society of Microcirculation and Vascular Biology (GfMVB) and the Swiss Society for Microcirculation and Vascular Research (SSMVR), Münster, Germany, Programme - Abstracts:35 (ID 23)

Eickholt C, Brunssen C, Langbein H, Brux M, Goettsch C, Goettsch W, Morawietz H (2014)
Importance of NOX4-generated H₂O₂ for regulation of endothelial function
8^th CRTD Summer Conference on Regenerative Medicine 2014, Dresden:ID65

Rissler J, Brunssen C, Langbein H, Hofmann A, Deussen A, Peitzsch M, Cimalla P, Koch E, Eisenhofer G, Morawietz H (2014)
Impact of mineralocorticoid receptor blockade on vascular function in atherosclerotic mouse models under high-fat diet
8^th CRTD Summer Conference on Regenerative Medicine 2014, Dresden:ID62

Morawietz H, Frenzel A, Mieting A, Goettsch W, Valtink M, Roehlecke C, Funk RHW, Becker KA, Engelmann K (2014)
VEGF-A expression under prodiabetic conditions in human retinal and endothelial cells and the vitreous fluid of patients with type 2 diabetes
8^th CRTD Summer Conference on Regenerative Medicine 2014, Dresden:ID61

Brunssen C, Rissler J, Langbein H, Hofmann A, Deussen A, Peitzsch M, Cimalla P, Koch E, Eisenhofer G, Morawietz H (2014)
Impact of mineralocorticoid receptor blockade on vascular function in atherosclerotic mouse models under high-fat diet
82^nd European Atherosclerosis Society (EAS) Congress, May 30-June 3, 2014, Madrid, Spain, Programme book:104, Abstract: 496, Poster: 150
Atherosclerosis 235(2):e152-e153 (EAS-0640)

Giebe S, Brunssen C, Brux M, Cockcroft N, Hewitt K, Morawietz H (2014)
Local hemodynamic forces and aqueous cigarette smoke extract affect development of endothelial dysfunction
82^nd European Atherosclerosis Society (EAS) Congress, May 30-June 3, 2014, Madrid, Spain, Programme book:87, Abstract: 352, Poster: 006
Atherosclerosis 235(2):e118 (EAS-0399)

Giebe S, Brunssen C, Brux M, Cockcroft N, Hewitt K, Morawietz H (2014)
Local hemodynamic forces and aqueous cigarette smoke extract affect development of endothelial dysfunction
Arteriosclerosis, Thrombosis, and Vascular Biology 2014 Scientific Sessions, May 1-3, 2014, Toronto, Ontario, Canada, Final Program and Abstracts:98
Arterioscler. Thromb. Vasc. Biol. 34 (Suppl 1):A660

Giebe S, Brunssen C, Brux M, Cockcroft N, Hewitt K, Morawietz H (2014)
Local hemodynamic forces and aqueous cigarette smoke extract affect development of endothelial dysfunction
The 9th International Symposium on Biomechanics in Vascular Biology and Cardiovascular Disease, Montreal, Canada, Program and Abstracts:90 (Poster Number 52)

Korten S, Brunssen C, Poitz DM, Großklaus S, Brux M, Schnittler HJ, Strasser RH, Bornstein SR, Goettsch W, Morawietz H (2014)
Impact of Hey2 and COUP-TFII on genes involved in arteriovenous differentiation and vascular development in human arterial and venous endothelial cells
Clin. Res. Cardiol. 103 (Suppl 1):V835

Rissler J, Brunssen C, Langbein H, Hofmann A, Deussen A, Peitzsch M, Eisenhofer G, Morawietz H (2014)
Influence of mineralocorticoid receptor blockade on vascular function and metabolic parameters in atherosclerotic mouse models with high-fat diet
Clin. Res. Cardiol. 103 (Suppl 1):P770

Brunssen C, Rissler J, Langbein H, Hofmann A, Deussen A, Peitzsch M, Cimalla P, Koch E, Eisenhofer G, Morawietz H (2014)
Influence of a mineralocorticoid receptor blockade on vascular function in atherosclerotic mouse models under high-fat diet
57. Symposium der Deutschen Gesellschaft für Endokrinologie 2014, Dresden
Exp. Clin. Endocrinol. Diabet. 122 (3): OP2_06

Engelmann F, Brunssen C, Brux M, Morawietz H (2014)
Analysis of 5‘ regulatory sequences of the human NADPH oxidase 4 gene in endothelial cells
93^rd Annual Meeting Deutsche Physiologische Gesellschaft 2014, Mainz, Abstracts
Acta Physiol. (Oxf.) 210 (Suppl 695):207 (P326)

Morawietz H, Frenzel A, Mieting A, Goettsch W, Valtink M, Roehlecke C, Funk RHW, Becker KA, Engelmann K (2013)
VEGF-A expression under prodiabetic conditions in human retinal and endothelial cells and in the vitreous fluid of patients with type 2 diabetes
93^rd Annual Meeting Deutsche Physiologische Gesellschaft 2014, Mainz, Abstracts
Acta Physiol. (Oxf.) 210 (Suppl 695):196 (P297)

Rissler J, Brunssen C, Langbein H, Hofmann A, Deussen A, Peitzsch M, Cimalla P, Koch E, Eisenhofer G, Morawietz H (2014)
Influence of a mineralocorticoid receptor blockade on vascular function in atherosclerotic mouse models under high-fat diet
93^rd Annual Meeting Deutsche Physiologische Gesellschaft 2014, Mainz, Abstracts
Acta Physiol. (Oxf.) 210 (Suppl 695):194 (P293)

Giebe S, Brunssen C, Brux M, Cockcroft N, Hewitt K, Morawietz H (2014)
Effects of shear stress and aqueous cigarette smoking extract on the development of endothelial dysfunction and plaque stability
93^rd Annual Meeting Deutsche Physiologische Gesellschaft 2014, Mainz, Abstracts
Acta Physiol. (Oxf.) 210 (Suppl 695):193-194 (P292)

Schubert U, Ludwig B, Lehmann S, Morawietz H, Bornstein SR (2014)
Engraftment, function and beta cell regulation in the adrenal transplant model
11. Deutsche Nebennierenkonferenz, Würzburg, January 24-26, 2013, Abstracts: 29
Award for best oral presentation

Rissler J, Brunssen C, Langbein H, Hofmann A, Deußen A, Peitzsch M, Eisenhofer G, Morawietz H (2014)
Influence of a mineralocorticoid receptor blockade on vascular function in atherosclerotic mouse models under high-fat diet
Final Retreat - Collegiate Members 2012/2013, Else Kröner-Promotionskolleg Dresden, January 10, 2014, Dresden, Abstracts:7-8

Publications 2013

Roehlecke C, Schumann U, Ader M, Brunssen C, Bramke S, Morawietz H, Funk RHW (2013)
Stress reaction in outer segments of photoreceptors after blue light irradiation
PLoS One 8(9):e71570. doi:10.1371/journal.pone.0071570 [https://www.ncbi.nlm.nih.gov/pubmed/24039718]

Korten S, Brunssen C, Poitz DM, Grossklaus S, Brux M, Schnittler HJ, Strasser RH, Bornstein SR, Morawietz H, Goettsch W (2013)
Impact of Hey2 and COUP-TFII on genes involved in arteriovenous differentiation in primary human arterial and venous endothelial cells
Basic Res. Cardiol. 108:362 (1-12). doi: 10.1007/s00395-013-0362-0 [https://www.ncbi.nlm.nih.gov/pubmed/23744056]

Morawietz H (2013)
Acromegaly and oxidative stress: impact on endothelial dysfunction and atherosclerosis
Horm. Metab. Res. 45:255-256. doi: http://dx.doi.org/10.1055/s-0033-1341495 [https://www.ncbi.nlm.nih.gov/pubmed/23608960]

Polanski AK, Ebner A, Ebner B, Hofmann A, Steinbronn N, Brandt A, Forkmann M, Tausche AK, Morawietz H, Strasser RH, Wunderlich C (2013)
Dexrazoxane prevents the development of the impaired cardiac phenotype in Caveolin-1 disrupted mice
J. Cardiovasc. Pharmacol. 61:545-552. doi: 10.1097/FJC.0b013e31828de47c [https://www.ncbi.nlm.nih.gov/pubmed/23474841]

Schubert U, Schmid J, Lehmann S, Zhang XY, Morawietz H, Block NL, Kanczkowski W, Schally AW, Bornstein SR, Ludwig B (2013)
Transplantation of pancreatic islets to adrenal gland is promoted by growth hormone releasing hormone agonists
Proc. Natl. Acad. Sci. U. S. A., 110:2288-2293. doi: 10.1073/pnas.1221505110 [https://www.ncbi.nlm.nih.gov/pubmed/23345449]

Morawietz H, Goettsch W, Brux M, Reimann M, Bornstein SR, Julius U, Ziemssen T (2013)    Lipoprotein apheresis of hypercholesterolemic patients mediates vasoprotective gene expression in human endothelial cells
Atherosclerosis (Supplements), 14:107-113, DOI: 10.1016/j.atherosclerosissup.2012.10.013 [https://www.ncbi.nlm.nih.gov/pubmed/23357151]

Abstracts 2013

Eickholt C, Brunssen C, Langbein H, Brux M, Goettsch C, Goettsch W, Morawietz H (2013)
Importance of NOX4-generated H₂O₂ for regulation of endothelial function
4^th Student Retreat, International PhD Program “Endothelium in Health & Disease”, November 8-9, 2013, Radebeul, Abstract book:15

Morawietz H, Goettsch W, Brux M, Reimann M, Bornstein SR, Julius U, Ziemssen T (2013)
Lipoprotein apheresis of hypercholesterolemic patients mediates vasoprotective gene expression in human endothelial cells
Congress of Clinical Chemistry and Laboratory Medicine / 10^th Annual Meeting of the German Society for Clinical Chemistry and Laboratory Medicine (DGKL), Dresden, Germany, 23rd–26th October, 2013
Clin. Chem. Lab. Med. 51(10):eA37-38

Rissler J, Brunssen C, Langbein H, Hofmann A, Deußen A, Peitzsch M, Eisenhofer G, Morawietz H (2013)
Influence of a mineralocorticoid receptor blockade and high-fat diet on vascular function in mouse models of atherosclerosis
2^nd Joint Meeting of the German Society of Microcirculation and Vascular Biology (GfMVB) and the Swiss Society for Microcirculation and Vascular Research (SSMVR), Dresden, Germany, Programme - Abstracts:110 O27 (ID 0028)

Morawietz H, Goettsch W, Brux M, Reimann M, Bornstein SR, Julius U, Ziemssen T (2013)
Lipoprotein apheresis of hypercholesterolemic patients mediates vasoprotective gene expression in human endothelial cells
2^nd Joint Meeting of the German Society of Microcirculation and Vascular Biology (GfMVB) and the Swiss Society for Microcirculation and Vascular Research (SSMVR), Dresden, Germany, Programme - Abstracts:85 P43 (ID 0002)

Korten S, Brunssen C, Poitz DM, Großklaus S, Brux M, Schnittler HJ, Strasser RH, Bornstein SR, Goettsch W, Morawietz H (2013)
Impact of Hey2 and COUP-TFII on genes involved in arteriovenous differentiation in primary human arterial and venous endothelial cells
2^nd Joint Meeting of the German Society of Microcirculation and Vascular Biology (GfMVB) and the Swiss Society for Microcirculation and Vascular Research (SSMVR), Dresden, Germany, Programme - Abstracts:78 P36 (ID 0001)

Catar RA, Goettsch C, Taye A, Hofmann A, Brunssen C, Muller G, Lehmann S, Schubert U, Ludwig B, Ziegler CG, Bornstein SR, Krug AW, Walther T, Morawietz H (2013)
Interaction between oxidized LDL, angiotensin II and oxidative stress
2^nd Joint Meeting of the German Society of Microcirculation and Vascular Biology (GfMVB) and the Swiss Society for Microcirculation and Vascular Research (SSMVR), Dresden, Germany, Programme - Abstracts:62 O11 (ID 0016)

Langbein H, Brunßen C, Hofmann A, Göttsch W, Cimalla P, Koch E, Morawietz H (2013)
A Novel In Vivo Method to Measure Endothelial Dysfunction in Mice after High-Fat Diet using Optical Coherence Tomography
2^nd Joint Meeting of the German Society of Microcirculation and Vascular Biology (GfMVB) and the Swiss Society for Microcirculation and Vascular Research (SSMVR), Dresden, Germany, Programme - Abstracts:59 P32 (ID 0022)

Frenzel A, Mieting A, Goettsch W, Valtink M, Roehlecke C, Funk RHW, Becker KA, Engelmann K, Morawietz H (2013)
VEGF-A in human retinal and endothelial cells, vascular sprouting and the vitreous fluid of patients with type 2 diabetes
2^nd Joint Meeting of the German Society of Microcirculation and Vascular Biology (GfMVB) and the Swiss Society for Microcirculation and Vascular Research (SSMVR), Dresden, Germany, Programme - Abstracts:38 P11 (ID 0052)

Lachmann P, Mayer S, Roeser M, Ishii S, Suh JM, Harlander S, Desch M, Brunssen C, Morawietz H, Tsai SY, Tsai MJ, Hohenstein B, Hugo C, Todorov VT (2013)
Renin gene expression is regulated by Chicken Ovalbumin Upstream Promoter Transcription Factor II (COUP-TF II)
Joint Annual Meeting of the ASPET/BPS at Experimental Biology (EB), Boston, MA
FASEB J. 27:1165.12

Rißler J, Brunßen C, Langbein H, Hofmann A, Deußen A, Morawietz H (2013)
Influence of a mineralocorticoid receptor blockade and high-fat diet on vascular function in atherosclerosis mouse models
7th CRTD Summer Conference on Regenerative Medicine 2013, Dresden:ID98

Langbein H, Leuner A, Goettsch W, Eickholt C, Cimalla P, Koch E, Morawietz H, Brunssen C (2013)
Optical Coherence Tomography as a novel method to measure endothelial dysfunction in mice in vivo after high-fat diet
7th CRTD Summer Conference on Regenerative Medicine 2013, Dresden:ID96

7th CRTD Summer Conference on Regenerative Medicine 2013, Dresden:ID94

Morawietz H, Catar RA, Goettsch C, Taye A, Hofmann A, Brunssen C, Muller G, Lehmann S, Schubert U, Ludwig B, Ziegler CG, Bornstein SR, Krug AW, Walther T (2013)
Cross-talk between oxidized LDL, angiotensin II and oxidative stress after AT₁ blockade and AT_1a/AT_1b double knockout
Endo 2013 The Endocrine Society’s 95^th Annual Meeting & Expo, San Francisco, CA
Endocr. Rev. 34 (03_MeetingAbstracts):FP40-5 (Featured Poster/Oral Session)
Endocr. Rev. 34 (03_MeetingAbstracts):MON-724 (Endo Poster Session)
Featured Poster Award

Schubert U, Ludwig B, Morawietz H, Bornstein SR (2013)
The adrenal gland and pancreatic islets. A beneficial endocrine alliance?
Endocr. Rev. 34 (03_MeetingAbstracts):OR13-5

Morawietz H, Goettsch W, Brux M, Reimann M, Bornstein SR, Julius U, Ziemssen T (2013)
Lipoprotein apheresis of hypercholesterolemic patients mediates vasoprotective gene expression in human endothelial cells
Arteriosclerosis, Thrombosis, and Vascular Biology 2013 Scientific Sessions, May 1-3, 2013, Lake Buena Vista, FL, Final Program and Abstracts:98
Arterioscler. Thromb. Vasc. Biol. 33:A395

Brunssen C, Eickholt C, Langbein H, Brux M, Hofmann A, Goettsch C, Goettsch W, Morawietz H (2013)
Regulation of endothelial nitric oxide synthase by NADPH oxidase 4 inhibition
The 8^th International Symposium on Biomechanics in Vascular Biology and Cardiovascular Disease, 18-19^th April 2013, Rotterdam, The Netherlands, Abstract book:22

Dosoki H, Stegemann A, Weiss N, Brunßen C, Morawietz H, Luger TA, Kerkhoff C, Bohm M (2013)
Nox4 - an emerging target for the future treatment of scleroderma
Exp. Dermatol. 22 (3):E15
Langbein H, Hofmann A, Goettsch W, Eickholt C, Cimalla P, Koch E, Brunßen C, Morawietz H (2013)
Optical Coherence Tomography as a novel method to measure endothelial dysfunction in mice in vivo after high-fat diet
Clin. Res. Cardiol. 102 (Suppl 1):P1087
Poster Award Vascular Signal Transduction and Metabolism

Langbein H, Hofmann A, Goettsch W, Eickholt C, Cimalla P, Koch E, Morawietz H, Brunssen C (2013)
Optical Coherence Tomography as a novel method to measure endothelial dysfunction in mice in vivo after high-fat diet
92^nd Annual Meeting Deutsche Physiologische Gesellschaft 2013, Heidelberg, Program & Abstracts
Acta Physiol. (Oxf.) 207 (Suppl 694):252 (P282)

Morawietz H, Goettsch W, Brux M, Reimann M, Bornstein SR, Julius U, Ziemssen T (2013)
Lipoprotein apheresis of hypercholesterolemic patients mediates vasoprotective gene expression in human endothelial cells
92^nd Annual Meeting Deutsche Physiologische Gesellschaft 2013, Heidelberg, Program & Abstracts
Acta Physiol. (Oxf.) 207 (Suppl 694):252 (P281)

Langbein H, Brunssen C, Hofmann A, Goettsch W, Cimalla P, Koch E, Morawietz H (2013)
NADPH oxidase 4 and endothelial dysfunction
3rd PhD Student Retreat, International PhD Program “Endothelium in Health & Disease”, January 11-12, 2013, Rathen, Abstract book:10

Brunssen C, Eickholt C, Langbein H, Brux M, Hofmann A, Morawietz H (2013)
Regulation of endothelial nitric oxide synthase by NADPH oxidase 4 inhibition
3rd PhD Student Retreat, International PhD Program “Endothelium in Health & Disease”, January 11-12, 2013, Rathen, Abstract book:9

Publications 2012

Mayer S, Roeser M, Lachmann P, Ishii S, Suh JM, Harlander S, Desch M, Brunssen C, Morawietz H, Tsai SY, Tsai MJ, Hohenstein B, Hugo C, Todorov VT (2012)
Chicken ovalbumin upstream promoter transcription factor II regulates renin gene expression
J. Biol. Chem., 287:24483-24491 [http://www.ncbi.nlm.nih.gov/pubmed/22645148]

Witt W, Jannasch A, Burkhard D, Christ T, Ravens U, Brunssen C, Leuner A, Morawietz H, Matschke K, Waldow T (2012)
Sphingosine-1-phosphate induces contraction of valvular interstitial cells from porcine aortic valves
Cardiovasc. Res., 93:490-497 [http://www.ncbi.nlm.nih.gov/pubmed/22232739]

Publications 2012

Abstracts 2012

Morawietz H, Eickholt C, Langbein H, Brux M, Goettsch C, Goettsch W, Arsov A, Brunssen C (2012)
Hydrogen peroxide releasing NADPH oxidase NOX4 is regulated by NRF2 in endothelial cells
Eur Heart J, (Suppl.), in press

Parshyna I, Lehmann S, Grahl K, Kühn C, Frenzel A, Weidlich H, Morawietz H (2012)
Adipose-derived stem cells, omega-3 fatty acids and angiogenesis
6th CRTD Summer Conference on Regenerative Medicine 2012, Dresden:ID64

Leuner A, Poitz DM, Brunssen C, Frenzel A, Ravens U, Strasser RH, Morawietz H (2012)
Oxidized LDL-cholesterol induces LOX-1 in macrophages and promotes endothelial dysfunction
6th CRTD Summer Conference on Regenerative Medicine 2012, Dresden:ID63

Langbein H, Leuner A, Brunssen C, Goettsch W, Eickholt C, Cimalla P, Koch E, Morawietz H (2012)
Vascular dysfunction caused by diet-induced obesity
6th CRTD Summer Conference on Regenerative Medicine 2012, Dresden:ID61

Eickholt C, Brunssen C, Langbein H, Brux M, Goettsch C, Goettsch W, Arsov A, Morawietz H (2012)
Hemodynamic regulation of NADPH oxidase NOX4 and NRF2 in endothelial cells: a novel feedback mechanism?
6th CRTD Summer Conference on Regenerative Medicine 2012, Dresden:ID60

Schubert U, Ludwig B, Steffen A, Schmid J, Morawietz H, Bornstein SR (2012)
The adrenal gland and pancreatic islets - a beneficial endocrine alliance?
6th CRTD Summer Conference on Regenerative Medicine 2012, Dresden:ID21

Brunssen C, Eickholt C, Langbein H, Brux M, Goettsch C, Goettsch W, Arsov A, Morawietz H (2012)
Activation of NRF2/ARE pathway regulates hydrogen peroxide releasing NADPH oxidase NOX4 in endothelial cells
Arterioscler, Thromb Vasc Biol, Scientific Sessions 2012, Chicago, IL, Final Program and Abstracts:157

Leuner A, Poitz DM, Augustin R, Neubauer H, Brunssen C, Ravens U, Strasser RH, Morawietz H (2012)
Oxidized LDL cholesterol induces endothelial dysfunction in the aorta and Lox-1 expression in macrophages
Arterioscler Thromb Vasc Biol, Scientific Sessions 2012, Chicago, IL, Final Program and Abstracts:79

Brunßen C, Arsov A, Eickholt C, Leuner A, Langbein H, Brux M, Goettsch C, Goettsch W, Augstein A, Poitz DM, Strasser RH, Breier G, Morawietz H (2012)
NADPH oxidase 4 is upregulated under chronic hypoxia by a HIF-independent mechanism in endothelial cells
Clin Res Cardiol 101 (Suppl 1):P1360

Brunßen C, Eickholt C, Langbein H, Brux M, Goettsch C, Goettsch W, Arsov A, Morawietz H (2012)
Regulation of endothelial NADPH oxidase NOX4 and NRF2 in response to hemodynamic forces by a novel feedback mechanism
Clin Res Cardiol 101 (Suppl 1):P909

Leuner A, Poitz DM, Brunssen C, Ravens U, Strasser RH, Morawietz H (2012)
Oxidized LDL-cholesterol induces endothelial dysfunction and LOX-1 in human macrophages
Frontiers in Cardiovascular Biology 2012, London,
Second Congress of the ESC Council on Basic Cardiovascular Science
Cardiovasc. Res., 93 (Suppl. 1):S117 (P599)

Morawietz H, Eickholt C, Langbein H, Brux M, Goettsch C, Goettsch W, Arsov A, Brunssen C (2012)
Regulation of endothelial NADPH oxidase NOX4 and NRF2 in response to hemodynamic forces by a novel feedback mechanism
Frontiers in Cardiovascular Biology, 30th March – 1st April 2012, London
Second Congress of the ESC Council on Basic Cardiovascular Science
Cardiovasc. Res., 93 (Suppl. 1):S60 (P302)

Langbein H, Leuner A, Brunssen C, Goettsch W, Eickholt C, Cimalla P, Koch E, Morawietz H (2012)
High-fat diet induces endothelial dysfunction in C57BL/6J mice
91st Annual Meeting Deutsche Physiologische Gesellschaft 2012, Dresden, Final Program & Abstracts:250 (P216)

Leuner A, Poitz DM, Brunssen C, Ravens U, Strasser RH, Morawietz H (2012)
Oxidized LDL-cholesterol induces LOX-1 in human macrophages and endothelial dysfunction in aortas
91st Annual Meeting Deutsche Physiologische Gesellschaft 2012, Dresden, Final Program & Abstracts:250 (P215)

Brunssen C, Arsov A, Eickholt C, Leuner A, Langbein H, Brux M, Goettsch C, Goettsch W, Augstein A, Poitz D, Strasser RH, Breier G, Morawietz H (2012)
NADPH oxidase 4 is upregulated under chronic hypoxia by a HIF-independent mechanism in endothelial cells
91st Annual Meeting Deutsche Physiologische Gesellschaft 2012, Dresden, Final Program & Abstracts:211 (P108)

Parshyna I, Lehmann S, Grahl K, Kühn C, Frenzel A, Weidlich H, Morawietz H (2012)
Adipose-derived stem cells, omega-3 fatty acids and angiogenesis
91st Annual Meeting Deutsche Physiologische Gesellschaft 2012, Dresden, Final Program & Abstracts:200 (P079)

Michelke L, Leuner A, Langbein H, Brunssen C, Bornstein SR, Morawietz H (2012)
Expression pattern of scavenger receptor LOX-1 in metabolic active tissues after high-fat diet feeding
91st Annual Meeting Deutsche Physiologische Gesellschaft 2012, Dresden, Final Program & Abstracts:180 (P024)

Dürbaum C, Leuner A, Brunssen C, Augstein A, Bornstein SR, Strasser RH, Morawietz H (2012)
Phenotype of the adipose tissue in atherosclerotic LDLR-/- mice after high-fat diet feeding
91st Annual Meeting Deutsche Physiologische Gesellschaft 2012, Dresden, Final Program & Abstracts:180 (P023)

Eickholt C, Brunssen C, Langbein H, Brux M, Goettsch C, Goettsch W, Arsov A, Morawietz H (2012)
NADPH oxidase NOX4 is regulated by the main mediator of cellular adaptation to oxidative stress NRF2
91st Annual Meeting Deutsche Physiologische Gesellschaft 2012, Dresden, Final Program & Abstracts:114 (S32)

Ludwig B, Morawietz H, Bornstein SR (2012)
The adrenal gland and pancreatic islands. A beneficial endocrine alliance?
10. Nebennierenkonferenz und Tagung der Sektion Nebenniere, Hypertonie und Steroide der Deutschen Gesellschaft für Endokrinologie 2012, Dresden, Abstracts:56

Taye A, Leuner A, Sawamura T, Morawietz H (2012)
Aldosterone increases LOX-1-mediated low-density lipoprotein uptake in human endothelial cells
10. Nebennierenkonferenz und Tagung der Sektion Nebenniere, Hypertonie und Steroide der Deutschen Gesellschaft für Endokrinologie 2012, Dresden, Abstracts:45

Publications 2011

Kampfrath T, Maiseyeu A, Ying Z, Shah Z, Deiuliis JA, Xu X, Kherada N, Brook RD, Reddy KM, Padture NP, Parthasarathy S, Chen LC, Moffatt-Bruce S, Sun Q, Morawietz H, Rajagopalan S (2011)
Chronic fine particulate matter exposure induces systemic vascular dysfunction via NADPH oxidase and TLR4 pathways
Circ. Res., 108:716-726 [http://www.ncbi.nlm.nihgov/pubmed/21273555]

Goettsch C, Goettsch W, Brux M, Haschke C, Brunssen C, Muller G, Bornstein SR, Duerrschmidt N, Wagner AH, Morawietz H (2011)
Arterial flow reduces oxidative stress via an antioxidant response element and Oct-1 binding site within the NADPH oxidase 4 promoter in endothelial cells
Basic Res. Cardiol., 106:551-561 [http://www.ncbi.nlm.nih.gov/pubmed/21399967]

Taye A, Morawietz H (2011)
Spironolactone inhibits NADPH oxidase-induced oxidative stress and enhances eNOS in human endothelial cells
Iran. J. Pharm. Res., 10:329-337 [http://ijpr.sbmu.ac.ir/]

Vleugels K, Schinner S, Krause D, Morawietz H, Bornstein SR, Ehrhart-Bornstein M, Krug AW (2011)
ERK1/2 MAPKs and Wnt signaling pathways are independently involved in adipocytokine-mediated aldosterone secretion
Exp. Clin. Endocrinol. Diabetes, 119:644-648 [http://www.ncbi.nlm.nih.gov/pubmed/21915818]

Morawietz H (2011)
Endothelial NADPH oxidases: friends or foes?
Basic Res. Cardiol., 106:521-525 [http://www.ncbi.nlm.nih.gov/pubmed/21559943]

Abstracts 2011

Brunssen C, Haschke C, Langbein H, Brux M, Goettsch C, Goettsch W, Arsov A, Morawietz H (2011)
The main mediator of cellular adaptation to redox stress NRF2 is regulated by NADPH oxidase NOX4 in endothelial cells: A novel feedback mechanism
Circulation, 124:A11900

Langbein H, Leuner A, Brunssen C, Goettsch W, Eickholt C, Cimalla P, Brandes RP, Koch E, Morawietz H (2011)
Endothelial function in different mice strains after high-fat diet
2nd PhD Student Retreat, International PhD Program “Endothelium in Health & Disease”, November 4-5, 2011, Meißen, Abstract book:22

Eickholt C, Brunssen C, Langbein H, Brux M, Goettsch C, Goettsch W, Arsov A, Morawietz H (2011)
Arterial flow induces cellular adaptation to redox stress via a novel feedback mechanism between transcription factor NRF2 and NADPH oxidase NOX4 in endothelial cells
2nd PhD Student Retreat, International PhD Program “Endothelium in Health & Disease”, November 4-5, 2011, Meißen, Abstract book:20

Brunssen C, Eickholt C, Langbein H, Brux M, Goettsch C, Goettsch W, Arsov A, Morawietz H (2011)
Hemodynamic regulation of NADPH oxidase NOX4 and NRF2 in endothelial cells: a novel feedback mechanism
Joint meeting European Society for Microcirculation (ESM) / German Society of Microcirculation and Vascular Biology (GfMVB) 2011, Munich, Abstract:P077
J Vasc Res, 48 (Suppl. 1):145

Eickholt C, Brunssen C, Langbein H, Brux M, Goettsch C, Goettsch W, Arsov A, Morawietz H (2011)
Arterial flow induces cellular adaptation to redox stress via a novel feedback mechanism between transcription factor NRF2 and NADPH oxidase NOX4 in endothelial cells
Summer School Inflammation and Cardiovascular Disease 2011, Obergurgl, Austria

Eickholt C, Brunssen C, Langbein H, Brux M, Goettsch C, Goettsch W, Arsov A, Morawietz H (2011)
The hemodynamic regulation of NADPH oxidase 4 and transcription factor NRF2 in endothelial cells: a novel feedback mechanism
5th CRTD Summer Conference on Regenerative Medicine 2011, Dresden:ID74

Langbein H, Leuner A, Brunssen C, Goettsch W, Eickholt C, Arsov A, Koch E, Morawietz H (2011)
Impact of physical activity in the atherosclerosis model of LDLR-/- mice
5th CRTD Summer Conference on Regenerative Medicine 2011, Dresden:ID72

Leuner A, Eichhorn B, Goettsch W, Brunssen C, Langbein H, Ravens U, Morawietz H (2011)
The Lox-1 receptor mediates obesity-derived oxidative stress
5th CRTD Summer Conference on Regenerative Medicine 2011, Dresden:ID71

Arsov A, Brunssen C, Haschke C, Leuner A, Langbein H, Brux M, Goettsch C, Goettsch W, Augstein A, Poitz D, Strasser RH, Breier G, Morawietz H (2011)
NADPH oxidase NOX4 in endothelial cells is upregulated under chronic hypoxia via HIF-independent mechanism
5th CRTD Summer Conference on Regenerative Medicine 2011, Dresden:ID70

Arsov A, Brunssen C, Haschke C, Leuner A, Langbein H, Brux M, Goettsch C, Goettsch W, Augstein A, Poitz D, Strasser RH, Breier G, Morawietz H (2011)
NADPH oxidase NOX4 in endothelial cells is upregulated under chronic hypoxia via HIF-independent mechanism
8th International Symposium on the Biology of Endothelial Cells, Zurich, Abstracts:73 (P57)

Langbein H, Leuner A, Brunssen C, Goettsch W, Haschke C, Arsov A, Walther J, Koch E, Morawietz H (2011)
Effects of physical activity in the atherosclerosis model of LDLR-/- mice
8th International Symposium on the Biology of Endothelial Cells, Zurich, Abstracts:61 (P45)

Brunssen C, Haschke C, Langbein H, Brux M, Goettsch C, Goettsch W, Arsov A, Morawietz H (2011)
The main mediator of cellular adaptation to redox stress NRF2 is regulated by NADPH oxidase NOX4 in endothelial cells: a novel feedback mechanism
8th International Symposium on the Biology of Endothelial Cells, Zurich, Abstracts:29 (P13)

Goettsch C, Goettsch W, Brux M, Haschke C, Brunssen C, Muller G, Bornstein SR, Duerrschmidt N, Wagner AH, Morawietz H (2011)
Arterial flow reduces oxidative stress via an antioxidant response element and Oct-1 binding site within the NADPH oxidase 4 promoter in human endothelial cells
Arterioscler Thromb Vasc Biol, Scientific Sessions 2011, Chicago,IL, Final Program and Abstracts:205

Leuner A, Eichhorn B, Goettsch W, Brunssen C, Langbein H, Ravens U, Morawietz H (2011)
The Lox-1 receptor as a link between obesity-derived oxidative stress
Arterioscler Thromb Vasc Biol, Scientific Sessions 2011, Chicago, IL, Final Program and Abstracts: 122-123

Goettsch W, Marton A, Goettsch C, Morawietz H (2011)
Balanced angiogenic potential: Cyclic strain downregulates angiopoietin-2 expression in human endothelial cells
Clin Res Cardiol, 100 (Suppl 1):P672

Leuner A, Eichhorn B, Goettsch W, Brunssen C, Langbein H, Bornstein SR, Ravens U, Morawietz H (2011)
The LOX-1 receptor as a novel link between obesity and atherosclerosis
54. Symposion der Deutschen Gesellschaft für Endokrinologie, Hamburg, Abstracts:PS2-03-9

Arsov A, Brunssen C, Haschke C, Leuner A, Langbein H, Goettsch C, Goettsch W, Augstein A, Poitz D, Strasser RH, Breier G, Morawietz H (2011)
Regulation of NADPH oxidase 4 in endothelial cells under hypoxia
Acta Physiol (Oxf), 201 (Suppl 682):230

Haschke C, Brunssen C, Goettsch C, Goettsch W, Brux M, Arsov A, Langbein H, Morawietz H (2011)
Regulation of NADPH oxidase 4 and transcription factor NRF2 by arterial flow in endothelial cells: a novel feed-back mechanism
Acta Physiol (Oxf), 201 (Suppl 682):213-214

Publications 2010

Kideryova L, Pytlik R, Benesova K, Vesela R, Karban J, Rychtrmocova H, Goettsch W, Morawietz H, Trneny M (2010)
Endothelial cells (EC) and endothelial precursor cells (EPC) kinetics in hematological patients undergoing chemotherapy or autologous stem cell transplantation (ASCT)
Hematol. Oncol., 28(4):192-201 [http://www.ncbi.nlm.nih.gov/pubmed/21136582]

Morawietz H (2010)
LOX-1 receptor as a novel target in endothelial dysfunction and atherosclerosis
Dtsch Med Wochenschr.;135:308-312 [http://www.ncbi.nlm.nih.gov/pubmed/20146162]

Helas S, Goettsch C, Schoppet M, Hempel U, Zeitz U, Morawietz H, Kostenuik PJ, Erben RG, Hofbauer LC (2010)
Prävention von Osteoporose und Gefäßkalzifizierung durch RANKL-Blockade mittels Denosumab in einem Mausmodell der Glukokortikoid-induzierten Osteoporose
Dtsch. Med. Wochenschr. 135 (Sonderausgabe Forschungspreise der Deutschen Gesellschaft für Innere Medizin – DGIM 2010):12 (Posterpreis) [http://www.dgim.de/portals/pdf/2010-08-23%20FINAL%20DGIM_Brosch%C3%BCre_gesamt.pdf]

Taye A, Saad AH, Kumar AH, Morawietz H (2010)
Effect of apocynin on NADPH oxidase-mediated oxidative stress-LOX-1-eNOS pathway in human endothelial cells exposed to high glucose
Eur. J. Pharmacol., 627(1-3):42-48 [http://www.ncbi.nlm.nih.gov/pubmed/19878672]

Clement HW, Vazquez JF, Sommer O, Heiser P, Morawietz H, Utzulino S, Fink B, Schulz E, von Dobschütz E (2010)
Lipopolysaccharide-induced radical formation in the striatum is abolished in Nox2/gp91phox deficient mice
J. Neural Transm., 117:13-22 [http://www.ncbi.nlm.nih.gov/pubmed/19866338]

Brunssen C, Korten S, Brux M, Seifert S, Roesler J, Bornstein S, Morawietz H, Goettsch W (2009)
COUP-TFII is regulated by high glucose in endothelial cells
Horm. Metab. Res., 42:81-87 [http://www.ncbi.nlm.nih.gov/pubmed/19862665]

Lehle K, Straub RH, Morawietz H, Kunz-Schughart L (2010)
Relevance of disease- and organ-specific endothelial cells for in vitro research
Cell Biol. Int., 34:1231-1238 [http://www.ncbi.nlm.nih.gov/pubmed/21067521]

Taye A, Sawamura T, Morawietz H (2010)
Aldosterone augments LOX-1-mediated low-density lipoprotein uptake in human umbilical artery endothelial cells
Pharmacol. Rep., 62:311-318 [http://www.ncbi.nlm.nih.gov/pubmed/20508287]

Walther J, Muller G, Morawietz H, Koch E (2010)
Signal power decrease due to fringe washout as an extension of the limited Doppler flow measurement range in spectral domain optical coherence tomography
J. Biomed. Opt., 15:041511-1-041511-11; DOI:10.1117/1.3466578 [http://www.ncbi.nlm.nih.gov/pubmed/20799789]

Cimalla P, Walther J, Goettsch W, Meissner S, Morawietz H, Koch E (2010)
Simultaneous dual-band optical coherence tomography as new tool for imaging vascular structure and function in the in vivo mouse model
Biomed. Tech., 55(Suppl. 1):1-4; DOI:10.11515/BMT.2010.153 [http://www.degruyter.com/view/j/bmte.2010.55issue-s1/issue-files/bmte.2010.55.issue-s1.xml]

Abstracts 2010

Walther J, Cimalla P, Goettsch W, Meissner S, Morawietz H, Koch E (2010)
Structural and functional in vivo imaging of the murine saphenous vessels by simultaneous dual-band optical coherence tomography
1st PhD Student Retreat, International PhD Program “Endothelium in Health & Disease”, December 3-4, 2010, Rathen, Abstract book:32

Leuner A, Eichhorn B, Goettsch W, Brunssen C, Ravens U, Morawietz H (2010)
The LOX-1 receptor as a link between adipose tissue and oxidative stress
1st PhD Student Retreat, International PhD Program “Endothelium in Health & Disease”, December 3-4, 2010, Rathen, Abstract book:22

Haschke C, Langbein H, Leuner A, Goettsch C, Goettsch W, Brunssen C, Morawietz H (2010)
Hemodynamic regulation of Nox4 in the endothelium
1st PhD Student Retreat, International PhD Program “Endothelium in Health & Disease”, December 3-4, 2010, Rathen, Abstract book:16

Brunssen C, Morawietz H, Goettsch W (2010)
High glucose regulates the transcription factor COUP-TFII in endothelial cells
1st PhD Student Retreat, International PhD Program “Endothelium in Health & Disease”, December 3-4, 2010, Rathen, Abstract book:9

Kampfrath T, Ying Z, Maiseyeu A, Shah Z, Deiuliis J, Morawietz H, Rajagopalan S (2010)
Chronic fine particulate matter exposure mobilizes CD11b+Ly6C+ monocytes and induces vascular dysfunction via TLR4 pathways
Circulation, 122 (Suppl.), abstract 2010-SS-A-21645-AHA

Arsov A, Brunssen C, Leuner A, Brux M, Haschke C, Goettsch C, Goettsch W, Morawietz H (2010)
Regulation of Nox4 in endothelial cells under hypoxia
26. Ernst Klenk Symposium in Molecular Medicine, NOX Family NADPH Oxidases as Therapeutic Targets, Cologne, Poster

Goettsch C, Goettsch W, Brunssen C, Brux M, Haschke C, Langbein H, Muller G, Bornstein SR, Duerrschmidt N, Wagner AH, Morawietz H (2010)
Arterial flow reduces oxidative stress via an antioxidant response element and Oct-1 binding site within the NADPH oxidase 4 promoter in endothelial cells
26. Ernst Klenk Symposium in Molecular Medicine, NOX Family NADPH Oxidases as Therapeutic Targets, Cologne, Poster

Morawietz H (2010)
Regulation of NAD(P)H oxidase by hemodynamic forces: impact on arteriosclerosis
J. Heart Dis., 7 (1):56

Leuner A, Eichhorn B, Ravens U, Morawietz H (2010)
Endothelial dysfunction in LOX-1 overexpressing mice
Cardiovasc. Res., 87 (Suppl. 1):S94

Goettsch W, Marton A, Goettsch C, Morawietz H (2010)
Cyclic strain downregulates angiopoietin-2 expression in human endothelial cells
Cardiovasc. Res., 87 (Suppl. 1):S55

Muller G, Walther J, Meissner S, Cuevas M, Goettsch C, Hofbauer LC, Koch E, Morawietz H (2010)
Doppler Fourier Domain Optical Coherence Tomography: A novel technique to analyze exercise-dependent changes in vascular dynamics in vivo
Jahrestagung der Gesellschaft für Mikrozirkulation und Vaskuläre Biologie, Berlin:41

Brunssen C, Korten S, Bornstein SR, Morawietz H, Goettsch W (2010)
High glucose regulates the transcription factor COUP-TFII in endothelial cells
Jahrestagung der Gesellschaft für Mikrozirkulation und Vaskuläre Biologie, Berlin:32

Parshyna I, Lehmann S, Grahl K, Kühn C, Weidlich H, Morawietz H (2010)
Impact of omega-3 fatty acids on adipose-derived stem cells and angiogenesis
3rd International Congress on Stem Cells and Tissue Formation, Dresden, poster

Parshyna I, Lehmann S, Grahl K, Kühn C, Weidlich H, Morawietz H (2010)
Angiogenic properties of adipose-derived stem cells: the role of omega-3 fatty acids
4th CRTD Summer Conference on Regenerative Medicine 2010, Dresden:ID85

Leuner A, Eichhorn B, Ravens U, Morawietz H (2010)
Altered endothelial function in the thoracic aorta of LOX-1 overexpressing mice
4th CRTD Summer Conference on Regenerative Medicine 2010, Dresden:ID84

Brunssen C, Korten S, Bornstein SR, Morawietz H, Goettsch W (2010)
COUP-TFII is regulated by glucose in endothelial cells
4th CRTD Summer Conference on Regenerative Medicine 2010, Dresden:ID78

Korten S, Poitz DM, Strasser RH, Bornstein SR, Goettsch W, Morawietz H (2010)
Hey2 and COUP-TFII play an important role in regulation of Notch pathway in primary human arterial and venous endothelial cells
Arterioscler. Thromb. Vasc. Biol., 30 (11):E264-E264

Leuner A, Eichhorn B, Goettsch W, Ravens U, Morawietz H (2010)
The LOX-1 receptor as link between atherosclerosis and glucose metabolism
6th World Congress on Prevention of Diabetes and its Complications, Dresden, Programme and Abstracts:167

Brunssen C, Korten S, Bornstein SR, Morawietz H, Goettsch W (2010)
High glucose regulates transcription factor COUP-TFII in venous endothelial cells
6th World Congress on Prevention of Diabetes and its Complications, Dresden, Programme and Abstracts:P-08-09

Korten S, Poitz DM, Strasser RH, Goettsch W, Morawietz H (2010)
Critical role of Hey2 and COUP-TFII in regulation of Notch pathway in primary human arterial and venous endothelial cells
Clin Res Cardiol 99 (Suppl 1):V1679

Morawietz H, Catar RA, Goettsch C, Taye A, Muller G, Ziegler CG, Bornstein SR, Krug AW, Walther T (2010)
Cross-talk between oxidized LDL, angiotensin II and oxidative stress after AT1 blockade and in AT1a/AT1b double knockout mice
Joint Annual Meetings of the Scandinavian and German Physiological Societies, Kopenhagen
Acta Physiol. (Oxf.), 198 (Suppl 677):175-176

Leuner A, Eichhorn B, Ravens U, Morawietz H (2010)
Altered endothelial function in the thoracic aorta of LOX-1 overexpressing mice
Joint Annual Meetings of the Scandinavian and German Physiological Societies, Kopenhagen
Acta Physiol. (Oxf.), 198 (Suppl 677):139-140

Korten S, Poitz DM, Strasser RH, Bornstein SR, Morawietz H, Goettsch W (2010)
Role of Hey2 and COUP-TFII in regulation of Notch pathway in human arterial and venous endothelial cells
53. Symposion der Deutschen Gesellschaft für Endokrinologie und Jahrestagung der Slowakischen Gesellschaft für Endokrinologie, Leipzig, Abstracts:PS2-03-7

Publications 2009

Helas S, Goettsch C, Schoppet M, Hempel U, Morawietz H, Kostenuik PJ, Erben RG, Hofbauer LC (2009)
Inhibition of receptor activator of NF-kB ligand by denosumab attenuated vascular calcium deposition in mice
Am. J. Pathol., 175:473-478

Meissner S, Mueller G, Walther J, Morawietz H, Koch E (2009)
In Vivo Fourier Domain Optical Coherence Tomography as new tool for investigation of vasodynamics in the mouse model
J. Biomed. Opt., 14:034027-1-034027-6; DOI:10.1117/1.3149865

Walther J, Mueller G, Morawietz H, Koch E (2009)
Analysis of in vitro and in vivo bidirectional flow velocities by phase-resolved Doppler Fourier-domain OCT
Sensors & Actuators: A. Physical, 156:14-21

Goettsch C, Goettsch W, Arsov A, Hofbauer LC, Bornstein SR, Morawietz H (2009)
Long-term cyclic strain downregulates endothelial Nox4
Antioxid. Redox Signal., 11:2385-2397

Eichhorn B, Muller G, Leuner A, Sawamura T, Ravens U, Morawietz H (2009)
Impaired vascular function in small resistance arteries of LOX-1 overexpressing mice on high-fat diet
Cardiovasc. Res., 82:493-502

Walther J, Mueller G, Morawietz H, Koch E (2009)
Quantifizierung von Flussgeschwindigkeiten mit dem Verfahren der Fourier Domain Optische Kohärenztomografie
Technisches Messen 76:198-210, DOI:10.1524/teme.2009.0938

Muller G, Meissner S, Walther J, Cuevas M, Koch E, Morawietz H (2009)
Analysis of murine vascular function in vivo by optical coherence tomography in response to high-fat diet
Horm. Metab. Res., 41:537-541

Goettsch C, Goettsch W, Muller G, Seebach J, Schnittler HJ, Morawietz H (2009)
Nox4 overexpression activates reactive oxygen species and p38 MAPK in human endothelial cells
Biochem. Biophys. Res. Commun., 380:355-360

Goette A, Bukowska A, Dobrev D, Pfeiffenberger J, Morawietz H, Strugala D, Wiswedel I, Röhl FW, Bergmann S, Bramlage P, Ravens U, Lendeckel U (2009)
Acute atrial tachyarrhythmia induces angiotensin II type 1 receptor mediated oxidative stress and microvascular flow abnormalities in the ventricles
Eur. Heart J., 30:1411-1420

Walther J, Muller G, Meissner S, Cimalla P, Homann H, Morawietz H, Koch E (2009)
Time-resolved blood flow measurement in the in vivo mouse model by optical frequency domain imaging
Proc. of SPIE-OSA Biomedical Optics, 7372:73720J-1-73720J-11, doi: 10.1117/12.831828

Muller G, Morawietz H (2009)
Nitric oxide, NAD(P)H oxidase and atherosclerosis
Antioxid. Redox Signal., 11:1711-1731

Morawietz H (2009)
Lipoproteine und Endothelfunktion bei kardiovaskulären Erkrankungen
Diabetes Stoffw. Herz, 18:99-104

Muller G Morawietz H (2009)
NAD(P)H oxidase and endothelial dysfunction
Horm. Metab. Res., 41:152-158

Abstracts 2009

Walther J, Muller G, Morawietz H, Koch E (2009)
Blood flow measurement in the in vivo mouse model by the combination of Doppler OCT and the signal power decrease in Spectral Domain OCT
European Conferences on Biomedical Optics (ECBO), München, Abstracts

Walther J, Muller G, Meissner S, Cimalla P, Homann H, Morawietz H, Koch E (2009)
Time-resolved blood flow measurement in the in vivo mouse model by optical frequency domain imaging
European Conferences on Biomedical Optics (ECBO), München, Abstracts

Morawietz H, Brunssen C, Gryczka C, Korten S, Goettsch W (2009)
Impact of growth factors, shear stress and transcription factor COUP-TFII on the Notch pathway in human endothelial cells
Circulation, 120 (Suppl.):S1133

Morawietz H, Catar RA, Goettsch C, Taye A, Muller G, Lehmann S, Ziegler CG, Bornstein SR, Krug AW, Walther T (2009)
Novel cross-talk between oxidized LDL, angiotensin II and oxidative stress after AT1 blockade and AT1a/AT1b double knockout
Circulation, 120 (Suppl.):S1133

Korten S, Goettsch W, Morawietz H (2009)
COUP-TFII inhibits expression of transcription factor Hey2 in human arterial endothelial cells
Circulation, 120 (Suppl.):S1004

Morawietz H, Muller G, Walther J, Cuevas M, Goettsch C, Hofbauer LC, Koch E (2009)
Doppler Fourier Domain Optical Coherence Tomography - A novel technique to analyze exercise-dependent changes in vascular dynamics of wild-type and LDL receptor knockout mice in vivo
Circulation, 120 (Suppl.):S533

Morawietz H (2009)
Oxidative stress and LOX-1 – impact on atherosclerosis
The Seventh – Krag – Atherothrombosis Conference, Krag, Poland
Czynniki Ryzyka, 3/09 (60):36

Goettsch C, Goettsch W, Arsov A, Hofbauer LC, Bornstein SR, Morawietz H (2009)
Downregulation of Nox4 by long term cyclic strain in human endothelial cells
J Vasc Res, 46 (Suppl 3):47

Leuner A, Eichhorn B, Ravens U, Morawietz H (2009)
Altered endothelial function in the thoracic aorta of LOX-1 overexpressing mice
J Vasc Res, 46 (Suppl 3):34

Goettsch C, Goettsch W, Arsov A, Hofbauer LC, Bornstein SR, Morawietz H (2009)
Long term cyclic strain downregulates Nox4 in human endothelial cells
7th International Symposium on the Biology of Endothelial Cells, Vienna, Abstracts:91

Korten S, Brunssen C, Goettsch W, Morawietz H (2009)
Inhibition of transcription factor Hey2 by COUP-TFII in arterial endothelial cells
7th International Symposium on the Biology of Endothelial Cells, Vienna, Abstracts:31

Walther J, Mueller G, Meissner S, Morawietz H, Koch E (2009)
Doppler Optische Kohärenztomografie der Blutflussgeschwindigkeiten im in vivo Mausmodell
Deutscher Anästhesiecongress 2009, Leipzig

Leuner A, Eichhorn B, Ravens U, Morawietz H (2009)
Vascular function of LOX-1 overexpressing mice on high-fat diet
3rd CRTD Summer Conference on Regenerative Medicine 2009, Dresden:ID82

Brunssen C, Gryczka C, Korten S, Morawietz H, Goettsch W (2009)
Regulation of Notch pathway genes by hypoxia, growth factors, shear stress and transcription factor COUP-TFII
3rd CRTD Summer Conference on Regenerative Medicine 2009, Dresden:ID73

Korten S, Brunssen C, Morawietz H, Goettsch W (2009)
Inhibition of transcription factor Hey2 in human arterial endothelial cells by COUP-TFII
3rd CRTD Summer Conference on Regenerative Medicine 2009, Dresden:ID72

Finger S, Goettsch C, Schoppet M, Zeitz U, Hempel U, Morawietz H, Kostenuik PJ, Erben RG, Hofbauer LC (2009)
Denosumab prevents bone loss and vascular calcium deposition in a murine model of glucocorticoid-induced osteoporosis
3rd CRTD Summer Conference on Regenerative Medicine 2009, Dresden:ID54

Finger S, Goettsch C, Schoppet M, Hempel U, Morawietz H, Kostenuik P, Erben R, Hofbauer L (2009)
Inhibition of RANK ligand prevents bone loss and vascular calcium deposition in a murine model of glucocorticoid-induced osteoporosis
Bone, 44(2):S447

Brunssen C, Korten S, Morawietz H, Goettsch W (2009)
Short-term high-glucose stimulation of human endothelial cells induces COUP-TFII expression
Arterioscler Thromb Vasc Biol, 29 (7):E90-E90

Korten S,Brunssen C, Morawietz H, Goettsch W (2009)
COUP-TFII inhibits expression of transcription factor Hey2 in human arterial endothelial cells
Arterioscler Thromb Vasc Biol, 29 (7):E89-E89

Kampfrath T, Ying Z, Morawietz H, Kherada N, Sun Q, Deiuliis JA, Rajagopalan S (2009)
Inhaled particulate matter <2.5 µm activates bone marrow-derived inflammatory monocytes through TLR4-dependent mechanisms
Arterioscler Thromb Vasc Biol, 29 (7):E63-E63

Brunssen C, Gryczka C, Korten S, Morawietz H, Goettsch W (2009)
Regulation of the Notch pathway genes by growth factors, shear stress, and transcription factor COUP-TFII
Arterioscler Thromb Vasc Biol, 29 (7):E57-E57

Muller G, Walther J, Meissner S, Cuevas M, Goettsch C, Hofbauer LC, Koch E, Morawietz H (2009)
Differences of murine vascular dynamics in LDLR knockout compared to C57BL/6 mice analyzed in vivo by Doppler Fourier Domain Optical Coherence Tomography
Arterioscler Thromb Vasc Biol, 29 (7):E56-E56

Morawietz H, Duerrschmidt N, Goettsch W, Muller G, Pagano PJ, Seebach J, Schnittler HJ, Wagner AH, Goettsch C (2009)
Shear stress, reactive oxygen species and the endothelium
The 4th International Symposium on Biomechanics in Vascular Biology and Cardiovascular Disease, 16-17th April 2009, Rotterdam, The Netherlands, Abstract book:9

Goettsch W, Brunßen C, Gryczka C, Korten S, Morawietz H (2009)
Arteriovenous Differentiation of Human Endothelial Cells: HEY2 contra COUP-TFII
Clin Res Cardiol (Z Kardiol), 98 (Suppl 1):V1197

Morawietz H (2009)
Endotheliale Dysfunktion und Atherosklerose
Z Geburtsh. Neonatol., 213:70

Mueller G, Meissner S, Walther J, Cuevas M, Koch E, Morawietz H (2009)
Influence of high-fat diet on murine vascular dynamics in LDLR knockout compared to C57BL/6 mice – analyzed by Doppler Fourier Domain Optical Coherence Tomography
Acta Physiol (Oxf), 195 (Suppl 669):148-149

Korten S, Morawietz H, Goettsch W (2009)
Chicken ovalbumin upstream promoter-transcription factor II (COUP-TFII) mediated downregulation of arterial transcription factor Hey2 in human endothelial cells
Acta Physiol (Oxf), 195 (Suppl 669):141

Eichhorn B, Mueller G, Leuner A, Sawamura T, Ravens U, Morawietz H (2009)
Impaired vascular function in small resistance arteries of LOX-1 overexpressing mice on high-fat diet
Acta Physiol (Oxf), 195 (Suppl 669):111

Brunssen C, Brux M, Morawietz H, Goettsch W (2009)
Glucose-dependent regulation of chicken ovalbumin upstream promoter-transcription factor II (COUP-TFII) in human endothelial cells
Acta Physiol (Oxf), 195 (Suppl 669):79

Publications 2008

Walther J, Muller G, Meissner S, Morawietz H, Koch E (2008)
Bildgebung der Vasomotorik und Quantifizierung der auftretenden Blutflussgeschwindigkeiten am in vivo Mausmodell mit dem Verfahren der Fourier Domain Optischen Kohärenztomographie
1.Dresdner Beiträge zur Medizintechnik: 2. Dresdner Medizintechnik-Symposium, Ed. by R. Poll, J. Füssel, E. Koch, TUDpress, Verlag der Wissenschaften GmbH, Dresden, 148-153

Walther J, Muller G, Cuevas M, Morawietz H, Koch E (2008)
Phase-resolved Doppler Fourier Domain Optical Coherence Tomography in the in vivo mouse model
ECIFMBE 2008, IFMBE Proceedings 22, Ed. by J. Vander Sloten, P. Verdonck, M. Nyssen, J. Haueisen, Springer-Verlag, Berlin-Heidelberg, 563-566

Morawietz H, Wagner AH, Hecker M, Goettsch W (2008)
Endothelin receptor B-mediated induction of c-jun and AP-1 in response to shear stress in human endothelial cells
Can. J. Physiol. Pharmacol., 86:499-504

Goettsch W, Schubert A, Morawietz H (2008)
Expression of human endothelin-converting enzyme isoforms: role of angiotensin II
Can. J. Physiol. Pharmacol., 86:299-309

Xu H, Goettsch C, Xia N, Horke S, Morawietz H, Forstermann U, Li H (2008)
Differential roles of PKC alpha and epsilon in controlling the gene expression of Nox4 in human endothelial cells
Free Radic. Biol. Med., 44:1656-1667

Wunderlich C, Schmeisser A, Heerwagen C, Ebner B, Schober K, Braun-Dullaeus RC, Schwencke C, Kasper M, Morawietz H, Strasser RH (2008)
Chronic NOS inhibition prevents adverse lung remodeling and pulmonary arterial hypertension in caveolin-1 knockout mice
Pulm. Pharmacol. Ther., 21:507-515

Goettsch W, Gryczka C, Korff T, Ernst E, Goettsch C, Seebach J, Schnittler HJ, Augustin HG, Morawietz H (2008)
Flow-dependent regulation of angiopoietin-2
J. Cell. Physiol., 214:491-503

Abstracts 2008

Muller G, Catar R, Goettsch C, Goettsch W, Bornstein S, Morawietz H (2008)
Obesity induces the endothelin system in the heart
Diabetes, Stoffwechsel und Herz, 17 (Suppl 1):S66-S67

Brunssen C, Seifert S, Roesler J, Bornstein S, Solimena M, Morawietz H, Goettsch W (2008)
COUP-TFII, an important regulator of glucose homeostasis, insulin sensitivity and vein identity, is down-regulated by high glucose in human venous endothelial cells
Diabetes, Stoffwechsel und Herz, 17 (Suppl 1):S69

Müller G, Meissner S, Walther J, Cuevas M, Koch E, Morawietz H (2008)
Repercussions of a high-fat diet on vascular dynamics in C57BL/6 mice
Diabetes, Stoffwechsel und Herz, 17 (Suppl 1):S72-S73

Walther J, Müller G, Cuevas M, Morawietz H, Koch E (2008)
Flow velocity analysis with phase-resolved Doppler Fourier Domain Optical Coherence Tomography
Eurosensors XXII, Dresden, Proceedings:236

Walther J, Cuevas M, Müller G, Morawietz H, Koch E (2008)
Quantifizierung von Flussgeschwindigkeiten mit dem Verfahren der Optischen Kohärenztomografie
XXII. Messtechnisches Symposium des Arbeitskreises der Hochschullehrer für Messtechnik e.V., Dresden

Walther J, Müller G, Meissner S, Morawietz H, Koch E (2008)
Bildgebung der Vasomotorik und Quantifizierung der auftretenden Blutflussgeschwindigkeiten am in vivo Mausmodell mit dem Verfahren der Fourier Domain Optischen Kohärenztomographie
2. Dresdner Medizintechnik-Symposium, Dresden

Francke A, Herold J, Mueller G, Meissner S, Miclea L, Niese U, Koch E, Morawietz H, Schmeisser A, Braun-Dullaeus R, Strasser RH (2008)
Optical Coherence Tomography (OCT) – A new method for in vivo imaging and quantification of collateral vessel growth in mice
Circulation, 118 (Suppl. 2):S519

Goettsch C, Goettsch W, Hofbauer LC, Arsov A, Morawietz H (2008)
Long term cyclic strain down-regulates the expression of the catalytic NADPH oxidase subunit Nox4 in human endothelial cells
Circulation, 118 (Suppl. 2):S316

Leuner A, Muller G, Catar RA, Goettsch C, Goettsch W, Bornstein SR, Morawietz H (2008)
Obesity induces the endothelin system in the heart
Annual Meeting of the Society for Microcirculation and Vascular Biology, Aachen, Germany, Program and Abstracts:105

Morawietz H, Catar RA, Muller G, Lehmann S, Goettsch C, Ziegler CG, Krug AW, Bornstein SR (2008)
AT1 blockade prevents lipoprotein-induced angiotensin II receptor 1 expression and oxidative stress
Annual Meeting of the Society for Microcirculation and Vascular Biology, Aachen, Germany, Program and Abstracts:68

Leuner A, Muller G, Morawietz H (2008)
Measurement of endothelial function using organ chamber experiments
46th Scientific Congress of the Society for Laboratory Animal Science and the 10th Advanced Training Course of the IGTp, Dresden, Abstracts:147 (Poster 4)

Walther J, Muller G, Meissner S, Morawietz H, Koch E (2008)
Doppler Optische Kohärenztomographie der Blutflussgeschwindigkeiten in der murinen Arteria saphena in vivo
46th Scientific Congress of the Society for Laboratory Animal Science and the 10th Advanced Training Course of the IGTp, Dresden, Abstracts:92 (Talk 34)

Muller G, Meissner S, Walther J, Cuevas M, Koch E, Morawietz H (2008)
In vivo analysis of murine vascular function by optical coherence tomography
46th Scientific Congress of the Society for Laboratory Animal Science and the 10th Advanced Training Course of the IGTp, Dresden, Abstracts:88 (Talk 32)

Leuner A, Muller G, Morawietz H (2008)
Transgenic mice and high-fat diet as models of atherosclerosis
46th Scientific Congress of the Society for Laboratory Animal Science and the 10th Advanced Training Course of the IGTp, Dresden, Abstracts:28 (Talk 2)

Morawietz H, Catar RA, Goettsch C, Ziegler CG, Krug AW, Bornstein SR, Muller G (2008)
Angiotensin II receptor 1 blockade reduces AT1 expression and oxidative stress after stimulation with lipoproteins
Eur Heart J, 29 (Suppl.):862

Morawietz H, Goettsch W, Müller G, Duerrschmidt N, Wagner AH, Goettsch C (2008)
Shear stress reduces endothelial oxidative stress via Nox4 and AP-1
Eur Heart J, 29 (Suppl.):788

Muller G, Catar RA, Goettsch C, Krug AW, Ziegler CG, Bornstein SR, Morawietz H (2008)
Angiotensin II receptor 1 blocker candesartan reduces lipoprotein-induced AT1 expression and oxidative stress
25th European Conference on Microcirculation, Budapest, Abstracts:60 (PHT 3)
J Vasc Res, 45 (Suppl. 2):89

Brunssen C, Roesler J, Morawietz H, Goettsch W (2008)
High glucose differentially regulates COUP-TFII in insulin-producing cells and venous endothelial cells
25th European Conference on Microcirculation, Budapest, Abstracts:57 (PDO 5)
J Vasc Res, 45 (Suppl. 2):84

Muller G, Meissner S, Walther J, Cuevas M, Koch E, Morawietz H (2008)
Influence of high-fat diet on vasodynamic parameters in different mouse strains
25th European Conference on Microcirculation, Budapest, Abstracts:23 (S11D)
J Vasc Res, 45 (Suppl. 2):24

Goettsch W, Gryczka C, Ellinghaus P, Morawietz H (2008)
Genes of the Notch pathway as markers of human arterial endothelial cells: Modulation by VEGF-A
XX International Congress of Genetics 2008, Berlin, Abstract book:290 (P343/37/B)

Krug AW, Kopprasch S, Dippong S, Catar R, Ziegler CG, Bornstein SR, Morawietz H, Gekle M (2008)
Rapid aldosterone-induced adhesion of leukocytes to endothelial cells
34th Meeting of the International Aldosterone Conference 2008, San Francisco, California:46

Leuner A, Arsov A, Lehmann S, Hultsch S, Goettsch C, Goettsch W, Muller G, Morawietz H (2008)
Low-density lipoproteins, renin-angiotensin system and oxidative stress: impact on endothelial function
2nd CRTD Summer Conference on Regenerative Medicine 2008, Dresden:ID68

Brunßen C, Goettsch W, Morawietz H (2008)
COUP-TFII as a regulator of glucose homeostasis and vein identity
2nd CRTD Summer Conference on Regenerative Medicine 2008, Dresden:ID30

Korten S, Morawietz H, Goettsch W (2008)
Transcription factors Hey2 and Coup-TFII as determinants of arterial-venous differentiation in human endothelial cells
2nd CRTD Summer Conference on Regenerative Medicine 2008, Dresden:ID10

Walther J, Muller G, Cuevas M, Morawietz H, Koch E (2008)
Blood flow measurement by Doppler Fourier Domain Optical Coherence Tomography in the in vivo mouse model
2nd CRTD Summer Conference on Regenerative Medicine 2008, Dresden:ID8
Poster Award Innovative Technologies

Muller G, Meissner S, Walther J, Cuevas M, Koch E, Morawietz H (2008)
In vivo imaging of murine vasodynamics analyzing different mouse strains by Optical Coherence Tomography
2nd CRTD Summer Conference on Regenerative Medicine 2008, Dresden:ID1

Muller G, Meissner S, Walther J, Cuevas M, Koch E, Morawietz H (2008)
Repercussions of a high-fat diet on vascular dynamics in C57BL/6 mice
3rd International Symposium on “The Metabolic Syndrome – a postprandial disease” 2008, Dresden, Germany
Diabetes, Stoffwechsel und Herz, 17 (Suppl):37-38

Brunssen C, Seifert S, Roesler J, Bornstein S, Solimena M, Morawietz H, Goettsch W (2008)
COUP-TFII, an important regulator of glucose homeostasis, insulin sensitivity and regulator of vein identity, is down-regulated by high glucose in human venous endothelial cells
3rd International Symposium on “The Metabolic Syndrome – a postprandial disease”, 2008, Dresden, Germany
Diabetes, Stoffwechsel und Herz, 17 (Suppl):34
Poster Award

Muller G, Catar RA, Goettsch C, Goettsch W, Bornstein SR, Morawietz H (2008)
Obesity induces the endothelin system in the heart
3rd International Symposium on “The Metabolic Syndrome – a postprandial disease”, 2008, Dresden, Germany, Final programme and list of abstracts
Diabetes, Stoffwechsel und Herz, 17 (Suppl):32

Morawietz H, Catar RA, Muller G, Goettsch C, Ziegler CG, Krug AW (2008)
Angiotensin II receptor 1 blockade reduces lipoprotein-induced AT1 expression and oxidative stress
EuroPrevent 2008, Paris, Abstract Book Supplement:87

Muller G, Meissner S, Walther J, Koch E, Morawietz H (2008)
In vivo imaging of murine vasodynamics analyzing different mouse strains by optical coherence tomography
Arteriosclerosis, Thrombosis, and Vascular Biology Annual Conference 2008: April 16–18, 2008, Atlanta, Georgia, USA
Arterioscler Thromb Vasc Biol, 28 (6):e-135

Morawietz H, Catar RA, Goettsch C, Ziegler CG, Krug AW, Muller G (2008)
Lipoprotein-induced angiotensin II receptor 1 expression and oxidative stress is reduced by AT1 blockade
Arterioscler Thromb Vasc Biol Annual Conference 2008, Atlanta, Georgia, USA
Arterioscler Thromb Vasc Biol, 28 (6):e-62

Catar RA, Muller G, Goettsch C, Krug AW, Ziegler C, Bornstein SR, Morawietz H (2008)
Angiotensin II Receptor 1 Blockade Reduces Lipoprotein-Induced AT1 Expression and Oxidative Stress
Clin Res Cardiol (Z Kardiol), 97 (Suppl 1):V1668

Goettsch W, Schubert A, Morawietz H (2008)
Expression of human endothelin-converting enzyme isoforms: role of angiotensin II
Clin Res Cardiol (Z Kardiol), 97 (Suppl 1):P881

Herold J, Muller G, Meissner S, Francke A, Miclea LC, Niese U, Koch E, Morawietz H, Schmeißer A, Strasser RH, Braun-Dullaeus R (2008)
Optical Coherence Tomography (OCT) a new method for in vivo imaging and quantification of hind limb perfusion in mice
Clin Res Cardiol (Z Kardiol), 97 (Suppl 1):P837

Muller G, Meißner S, Krüger A, Koch E, Morawietz H (2008)
In vivo imaging of vasodynamics after high-fat diet by FD-Optical Coherence Tomography
Clin Res Cardiol (Z Kardiol), 97 (Suppl 1):P836
Prämiertes Poster

Leuner A, Muller G, Morawietz H (2008)
Impaired vascular function in p47phox knockout mice on high-fat diet
Clin Res Cardiol (Z Kardiol), 97 (Suppl 1):P785

Bergmann S, Gehrisch S, Siegert G, Meinhardt M, Gräßler J, Morawietz H, Baretton G (2008)
Experience with different forms of assessment used in a 9-week PBL course
Naresuan-Dresden-Burapha International Workshop on Medical Education, Phuket, Thailand, Proceedings:14-16

Goettsch C, Hofbauer LC, Morawietz H (2008)
Long-term cyclic strain down-regulates endothelial oxidative stress via Nox4
Acta Physiol (Oxf), 192 (Suppl 663):193

Muller G, Catar RA, Goettsch C, Goettsch W, Bornstein SR, Morawietz H (2008)
Obesity induces the cardiac endothelin system
Acta Physiol (Oxf), 192 (Suppl 663):186

Leuner A, Muller G, Morawietz H (2008)
Impact of high-fat diet on endothelial function in p47phox knockout mice
Acta Physiol (Oxf), 192 (Suppl 663):186

Müller G, Meissner S, Krueger A, Koch E, Morawietz H (2008)
Influence of high-fat diet on vascular dynamics in C57BL/6 mice – analyzed in vivo by OCT
Acta Physiol (Oxf), 192 (Suppl 663):185

Goettsch W, Schubert A, Morawietz H (2008)
Expression of endothelin-converting enzyme isoforms: role of renin-angiotensin system
Acta Physiol (Oxf), 192 (Suppl 663):110

Gryczka C, Brunssen C, Korten S, Morawietz H, Goettsch W (2008)
Genes of the Notch pathway as markers of human arterial endothelial cells: modulation by VEGF-A
Acta Physiol (Oxf), 192 (Suppl 663):80

Catar RA, Muller G, Goettsch C, Krug AW, Ziegler C, Bornstein SR, Morawietz H (2008)
Angiotensin II receptor 1 blockade reduces lipoprotein-induced AT1 expression and oxidative stress
Acta Physiol (Oxf), 192 (Suppl 663):75

Publications 2007

Krug AW, Kopprasch S, Ziegler CG, Dippong S, Catar RA, Bornstein SR, Morawietz H, Gekle M (2007)
Aldosterone rapidly induces leukocyte adhesion to endothelial cells: a new link between aldosterone and arteriosclerosis?
Hypertension, 50:e156-e157 (cover picture)

Walther J, Meißner S, Muller G, Krüger A, Morawietz H, Koch E (2007)
Vasodynamics of the murine arteria saphena by Optical Coherence Tomography
Proceedings in Physics 114: Advances in Medical Engineering, Ed. by T. M. Buzug, D. Holz, S. Weber, J. Bongartz, M. Kohl-Bareis, U. Hartmann, Springer-Verlag, Berlin-Heidelberg-New York, 64-68

Catar RA, Muller G, Heidler J, Schmitz G, Bornstein SR, Morawietz H (2007)
Low-density lipoproteins induce the renin-angiotensin system and their receptors in human endothelial cells
Horm. Metab. Res., 39:801-805

Kanczkowski W, Morawietz H, Ziegler CG, Funk RH, Schmitz G, Zacharowski K, Mohn CE, Ehrhart-Bornstein M, Bornstein SR (2007)
Pam3CSK4 and LTA – TLRs ligands associated with microdomains induce IL8 production in human adrenocortical cancer cells
Horm. Metab. Res., 39:457-460

Morawietz H (2007)
LOX-1 and atherosclerosis: proof of concept in LOX-1-knockout mice
Circ. Res., 100:1534-1536

Morawietz H (2007)
Schwerpunkt Alternsforschung: Die Methusela-Mutation neutralisiert Alters-Radikale
Cardio News, 10 (3):23

Morawietz H (2007)
Sauerstoffradikale in der Gefäßwand: Oxidativer Stress und endotheliale Dysfunktion
MedReport, 31 (2):3

Morawietz H (2007)
Going with the flow: Just say NO to oxygen radicals
Physiology News, 66:30-31

Muller G, Goettsch C, Morawietz H (2007)
Oxidative stress and endothelial dysfunction
Hämostaseologie, 27:5-12

Morawietz H (2007)
Antioxidative defense in endothelial cells: New kids on the block
Thromb. Haemost., 97:3-4

Abstracts 2007

Goettsch W, Gryczka C, Korff T, Ernst E, Goettsch C, Seebach J, Schnittler HJ, Augustin HG, Morawietz H (2007)
Flow-dependent regulation of angiopoietin-2
Circulation, 116 (Suppl.):II-73

Clement HW, Sommer O, Utzolino S, Morawietz H, Hopt UT, von Dobschuetz E (2007)
Response of central nervous formated ROS and IL6 to endotoxin released by gp91(phox)-containing NADPH oxidase
Free Radic. Biol. Med., 43 (Suppl 1):S144

Meissner S, Muller G, Walther J, Kruger A, Cuevas M, Eichhorn B, Ravens U, Morawietz H, Koch E (2007)
Investigation of murine vasodynamics by Fourier Domain Optical Coherence Tomography
Proceedings of the Society of Photo-Optical Instrumentation Engineers (SPIE): Optical coherence tomography and coherence techniques III, Ed. by Andersen PE, Chen Z, 6627:D6270

Goettsch W, Gryczka C, Korten S, Korff T, Ernst E, Goettsch C, Seebach J, Schnittler HJ, Augustin HG, Morawietz H (2007)
Shear stress-dependent regulation of angiopoietin-2
Joint Meeting of the Society for Microcirculation and Vascular Biology and the 6th International Symposium on the Biology of Endothelial Cells, Heidelberg, Germany, Programme and Abstracts: 146

Leuner A, Müller G, Morawietz H (2007)
Impact of high-fat diet on endothelial function in p47phox knockout mice
Joint Meeting of the Society for Microcirculation and Vascular Biology and the 6th International Symposium on the Biology of Endothelial Cells, Heidelberg, Germany, Programme and Abstracts: 145

Goettsch C, Goettsch W, Müller G, Duerrschmidt N, Wagner AH, Morawietz H (2007)
Shear stress-related reduction in endothelial oxidative stress from Nox4 and AP-1
Joint Meeting of the Society for Microcirculation and Vascular Biology and the 6th International Symposium on the Biology of Endothelial Cells, Heidelberg, Germany, Programme and Abstracts: 26

Brunssen C, Goettsch W, Gryczka C, Brux M, Korff T, Ernst E, Goettsch C, Seebach J, Schnittler HJ, Augustin HG, Morawietz H (2007)
Regulation of Angiopoietin-2 in human endothelial cells by shear stress
1st International Kloster Seeon Meeting of the DFG SPP1190 "The tumor - vessel interface: Cellular and molecular mechanisms of tumor progression and metastasis", Kloster Seeon, Germany, Abstracts:31

Muller G, Catar RA, Goettsch W, Morawietz H (2007)
Obesity induces the endothelin system in the murine heart
10th International Conference on Endothelin, Bergamo, Italy, Book of Abstracts:P-084, 105 (Highlighted Poster)

Goettsch W, Schubert A, Morawietz H (2007)
Expression of human endothelin-converting enzyme isoforms: role of angiotensin II
10th International Conference on Endothelin, Bergamo, Italy, Book of Abstracts:P-029, 75

Morawietz H, Wagner AH, Hecker M, Goettsch W (2007)
Endothelin receptor B-mediated induction of c-jun and AP-1 in response to shear stress in human endothelial cells
10th International Conference on Endothelin, Bergamo, Italy, Book of Abstracts:P-004, 62

Muller G, Meissner S, Krueger A, Eichhorn B, Ravens U, Koch E, Morawietz H (2007)
In vivo imaging of vasodynamics after high fat diet by FD-Optical Coherence Tomography in mice
4th European Meeting on Vascular Biology and Medicine, Bristol, UK, Programme, P122:38

Goettsch C, Goettsch W, Muller G, Duerrschmidt N, Wagner A, Morawietz H (2007)
Flow-related reduction in oxidative stress from Nox4 and AP-1 in endothelial cells
4th European Meeting on Vascular Biology and Medicine, Bristol, UK, Programme, P161:48 Highlighted Poster (Top 10 in Europe)

Muller G, Meissner S, Walther J, Krueger A, Eichhorn B, Ravens U, Koch E, Morawietz H (2007)
Vasodynamics of mice analyzed by optical coherence tomography in vivo
Frontiers of cellular, developmental and molecular biology, European Life Science Organization 2007 Meeting, Dresden, ELSO 2007 Proceedings:141

Morawietz H, Erbs S, Holtz J, Schubert A, Goettsch W, Adams V, Mohr FW, Schuler G, Hambrecht R (2007)
Endothelial Protection, AT1 blockade and Cholesterol-Dependent Oxidative Stress: The EPAS trial
Eur. Heart J., (Suppl.), 28 (Suppl.):220

Hagen B, Müller G, Morawietz H (2007)
Serum of patients with antiphospholipid syndrome induces adhesion molecules in endothelial cells
1st Japanese–Polish–German Joint Meeting on Coagulation and Fibrinolysis, Dresden, Program and Abstracts: 6

Muller G, Meißner S, Walther J, Krüger A, Koch E, Morawietz H (2007)
Optical coherence tomography as new tool for analysing vascular function in vivo
CRTD Summer Conference on Regenerative Therapies 2007, Dresden, E9

Korten S, Brunssen S, Goettsch W, Morawietz H (2007)
Arteriovenous differentiation of human endothelial cells
CRTD Summer Conference on Regenerative Therapies 2007, Dresden, E1 (Cover picture programme)

Eichhorn B, Muller G, Morawietz H, Ravens U (2007)
Overexpression of the LOX-1 receptor affects contractile and electrophysiological function in small arteries
J. Mol. Cell. Cardiol., 42 (Suppl 1): S221

Muller G, Meissner S, Krueger A, Eichhorn B, Ravens U, Koch E, Morawietz H (2007)
In vivo imaging of murine vasodynamics by Fourier Domain Optical Coherence Tomography
Arterioscler. Thromb. Vasc. Biol., 27 (6):e131-e132

Muller G, Eichhorn B, Ravens U, Schrock E, Sawamura T, Morawietz H (2007)
Vascular function of LOX-1 overexpressing mice on high-fat diet
Arterioscler. Thromb. Vasc. Biol., 27 (6):e93

Eichhorn B, Muller G, Morawietz H, Ravens U (2007)
Contractile and electrophysiological function in small arteries from LOX-1 overexpressing mice
Naunyn Schmiedebergs Arch. Pharmacol., 375 (Suppl. 1):23

Goettsch C, Catar R, Muller G, Wingler K, Scheurer P, Schmidt H, Morawietz H (2007)
Nox inhibitor VAS2870 reduces oxLDL-mediated oxidative stress in human endothelial cells
Clin. Res. Cardiol., 96 (Suppl 1):P1219

Morawietz H, Erbs S, Holtz J, Schubert A, Krekler M, Goettsch W, Adams V, Lenk K, Mohr FW, Schuler G, Hambrecht R (2007)
Endothelial Protection, AT1 blockade and Cholesterol-Dependent Oxidative Stress: The EPAS trial
Clin. Res. Cardiol., 96 (Suppl 1):P528

Goettsch C, Muller G, Goettsch W, Wagner A, Morawietz H (2007)
Nox4 promoter activity is downregulated by an AP-1-mediated mechanism in response to laminar shear stress in human endothelial cells
Clin. Res. Cardiol., 96 (Suppl 1):V45

Muller G, Meißner S, Krüger A, Eichhorn B, Ravens U, Koch E, Morawietz H (2007)
In vivo analysis of vascular function using optical coherence tomography
Acta Physiol. (Oxf.), 189 (Suppl 653):152

Goettsch C, Catar RA, Muller G, Wingler K, Scheurer P, Schmidt HHHW, Morawietz H (2007)
The novel Nox inhibitor VAS2870 prevents oxLDL-induced reactive oxygen species formation in HUVEC
Acta Physiol (Oxf), 189 (Suppl 653):145

Brunssen C, Goettsch W, Brux M, Seifert S, Roesler J, Morawietz H (2007)
Long-term insulin stimulation stabilizes COUP-TFII protein in human arterial endothelial cells (HUAEC)
Acta Physiol. (Oxf.), 189 (Suppl 653):144

Hagen B, Muller G, Morawietz H (2007)
Serum of patients with antiphospholipid syndrome induces adhesion molecules in endothelial cells
Acta Physiol. (Oxf.), 189 (Suppl 653):142

Goettsch W, Brux M, Gryczka C, Morawietz H (2007)
FOXO1 translocation after shear stress regulates Ang-2 expression in human endothelial cells
Acta Physiol. (Oxf.), 189 (Suppl 653):141

Goettsch C, Goettsch W, Muller G, Duerrschmidt N, Wagner A, Morawietz H (2007)
Reduced oxidative stress by flow in endothelial cells through Nox4 and AP-1
Acta Physiol. (Oxf.), 189 (Suppl 653):77

Catar RA, Müller G, Heidler J, Morawietz H (2007)
Low-density lipoproteins induce the renin-angiotensin system and their receptors in human endothelial cells
Acta Physiol. (Oxf.), 189 (Suppl 653):68

Morawietz H (2007)
Oxidative stress and endothelial dysfunction
Hämostaseologie, 27:A14

Publications 2006

Morawietz H, Rohrbach S, Rueckschloss U, Schellenberger E, Hakim K, Zerkowski H-R, Kojda G, Darmer D, Holtz J (2006)
Increased cardiac endothelial nitric oxide synthase expression in patients with angiotensin-converting enzyme inhibitor therapy
Eur. J. Clin. Invest., 36:705-712

Duerrschmidt N, Stielow C, Muller G, Pagano PJ, Morawietz H (2006)
NO-mediated regulation of NAD(P)H oxidase by laminar shear stress in human endothelial cells.
J Physiol., 576:557-567

Meißner S, Muller G, Eichhorn B, Popp A, Morawietz H, Ravens U, Koch E (2006)
Optische Kohärenztomografie der Vasodilatation und Vaskonstriktion an der murinen Arteria saphena
Dresdner Beiträge zur Medizintechnik: 1. Dresdner Medizintechnik-Symposium, R. Poll, J. Füssel, Ed., TUDpress, Dresden), 61-66

Morawietz H (2006)
Workshop „Schubspannung an Endothelzellen“ in Dresden
Dresdner Universitätsjournal, 17(19):2

Morawietz H, Erbs S, Holtz J, Schubert A, Krekler M, Goettsch W, Kuss O, Adams V, Lenk K, Mohr FW, Schuler G, Hambrecht R (2006)
Endothelial protection, AT1 blockade and cholesterol-dependent oxidative stress: The EPAS trial
Circulation, 114:I296-301

Morawietz H, Breier G (2006)
Endothelial cell biology: an update - 5th International Symposium on the Biology of Endothelial Cells
Thromb. Haemost., 95:1025-1030

Muller G, Catar RA, Niemann B, Barton M, Knels L, Wendel M, Morawietz H (2006)
Upregulation of endothelin receptor B in human endothelial cells by low-density lipoproteins
Exp. Biol. Med., 231:766-771

Stielow C, Catar RA, Muller G, Wingler K, Scheurer P, Schmidt HHHW, Morawietz H (2006)
Novel Nox inhibitor of oxLDL-induced reactive oxygen species formation in human endothelial cells
Biochem. Biophys. Res. Commun., 344:200-205

Morawietz H, Bornstein SR, Dong F, Zhang X, Ren J (2006)
Leptin, endothelin, NADPH oxidase, and heart failure
Hypertension, 47:e20-e21

Korff T, Dandekar G, Pfaff D, Füller T, Goettsch W, Morawietz H, Schaffner F, Augustin HG (2006)
Endothelial ephrinB2 is controlled by microenvironmental determinants and associates context-dependently with CD31
Arterioscler. Thromb. Vasc. Biol., 26:468-74

Abstracts 2006

Stielow C, Muller G, Goettsch W, Wagner A, Morawietz H (2006)
AP-1-mediated downregulation of Nox4 promoter activity by laminar shear stress in human endothelial cells
Circulation, 114 (Suppl.):II-119

Stielow C, Catar RA, Muller G, Wingler K, Scheurer P, Schmidt HHHW, Morawietz H (2006)
Novel Nox inhibitor VAS2870 prevents oxLDL-induced reactive oxygen species formation in endothelial cells
J Vasc Res, 43 (6):571

Morawietz H, Erbs S, Holtz J, Schubert A, Krekler M, Goettsch W, Kuss O, Adams V, Lenk K, Mohr FW, Schuler G, Hambrecht R (2006)
Endothelial protection, AT1 blockade and cholesterol-dependent oxidative stress: The EPAS trial
J Vasc Res, 43 (6):570-571

Catar RA, Muller G, Morawietz H (2006)
Low-density lipoproteins induce the renin-angiotensin and endothelin system and their receptors in human endothelial cells
Diabetes, Stoffwechsel und Herz, 15 (Suppl 2):LB6/24

Morawietz H, Erbs S, Holtz J, Schubert A, Krekler M, Goettsch W, Adams V, Lenk K, Mohr FW, Schuler G, Hambrecht R (2006)
Endothelial protection, AT1 blockade and cholesterol-dependent oxidative stress: The EPAS trial
J Vasc Res, 43 (Suppl 1):18

Gryczka C, Goettsch W, Morawietz H (2006)
Die Regulation von Angiopoietin-2 durch Schubspannung ist VEGF-vermittelt
72. Jahrestagung der Deutschen Gesellschaft für Kardiologie-Herz- und Kreislaufforschung, Mannheim, Abstracts: V796

Stielow C, Müller G, Morawietz H (2006)
Rolle von Nox-Isoformen bei der NAD(P)H-Oxidase vermittelten Superoxidanion-Bildung in humanen Endothelzellen
72. Jahrestagung der Deutschen Gesellschaft für Kardiologie-Herz- und Kreislaufforschung, Mannheim, Abstracts: V251

Eichhorn B, Müller G, Jürgens S, Sawamura T, Morawietz H, Ravens U (2006)
Overexpression of the LOX-1 receptor affects vascular function in small arteries
N.-S. Arch. Pharmacol., 372 (Suppl 1):36

Müller G, Eichhorn B, Ravens U, Schröck E, Sawamura T, Morawietz H (2006)
Vascular function of LOX-1 overexpressing mice
Acta Physiol. (Oxf.), 186 (Suppl 1): 254

Goettsch W, Gryczka C, Morawietz H (2006)
Shear stress regulation of Ang-2 involves VEGF
Acta Physiol. (Oxf.), 186 (Suppl 1):203

Müller G, Stielow C, Morawietz H (2006)
Improved vascular function in Nox2 knockout mice
Acta Physiol. (Oxf.), 186 (Suppl 1):142

Morawietz H, Erbs S, Holtz J, Schubert A, Krekler M, Goettsch W, Adams V, Mohr FW, Schuler G, Hambrecht R (2006)
Endothelial Protection, AT1 blockade and Cholesterol-Dependent Oxidative Stress: The EPAS trial
Acta Physiol. (Oxf.), 186 (Suppl 1):102

Catar RA, Müller G, Niemann B, Barton M, Knels L, Wendel M, Morawietz H (2006)
Upregulation of endothelin receptor B by low-density lipoproteins in human endothelial cells
Acta Physiol. (Oxf.), 186 (Suppl 1):93

Stielow C, Müller G, Morawietz H (2006)
Nox4-mediated superoxide anion formation in human endothelial cells
J. Vasc. Res., 43:28-29

Publications 2005

Niemann B, Rohrbach S, Catar RA, Muller G, Barton M, Morawietz H (2005)
Native and oxidized low-density lipoproteins stimulate endothelin-converting enzyme-1 expression in human endothelial cells
Biochem. Biophys. Res. Commun., 334:747-753

Bornstein SR, Morawietz H (2005)
Toll-like receptors, endocrine stress response, and arteriosclerosis
Arterioscler. Thromb. Vasc. Biol., 25:e135

Wunder C, Brock RW, Frantz S, Göttsch W, Morawietz H, Roewer N, Eichelbronner O (2005)
Carbon monoxide, but not endothelin-1, plays a major role for the hepatic microcirculation in a murine model of early systemic inflammation
Crit. Care Med., 33:2323-2331

Morawietz H (2005)
Induktion von Transkriptionsfaktoren durch Schubspannung in humanen Endothelzellen
„Spitzenforschung Herz-Kreislaufmedizin. Auszeichnungen, Fördermöglichkeiten und Innovationen“, Ed. by D. Herrmann, ALPHA-Informations-GmbH, Lampertheim, 62-69

Morawietz H (2005)
Beyond blood pressure: endothelial protection against hypercholesterolemia by angiotensin II type-1 receptor blockade
Invited Editorial Commentary
Hypertension, 45:185-186

Morawietz H (2005)
Morawietz, Henning
„Die Professoren der Medizinischen Fakultät Carl Gustav Carus Dresden und ihrer Vorgängereinrichtungen 1814-2004“, Ed. by C.-P. Heidel, M. Lienert, K. G. Saur-Verlag, München, 155-156

Morawietz H, Schubert A (2005)
Biomechanical stimulation of vascular cells in vitro
„Practical Methods in Cardiovascular Research“, Ed. by S. Dhein, F.-W. Mohr, M. Delmar, Springer-Verlag, Berlin-Heidelberg-New York, 813-828

Ellinghaus P, Scheubel RJ, Dobrev D, Ravens U, Holtz J, Huetter J, Nielsch U, Morawietz H (2005)
Comparing the global mRNA expression profile of human atrial and ventricular myocardium with high-density oligonucleotide arrays
J. Thorac. Cardiovasc. Surg., 129:1383-1390

Abstracts 2005

Morawietz H, Erbs S, Holtz J, Schubert A, Krekler M, Goettsch W, Adams V, Lenk K, Mohr FW, Schuler G, Hambrecht R (2005)
Endothelial protection, AT1 blockade and cholesterol-dependent oxidative stress: The EPAS trial
Circulation, 112 (Suppl.):II-441

Popp A, Müller G, Morawietz H, Koch E (2005)
In situ optical coherence tomography of murine blood vessels
5th International Symposium on the Biology of Endothelial Cells, Dresden, Abstracts: 79

Gryczka C, Goettsch W, Augustin HG, Morawietz H (2005)
Shear stress-dependent regulation of Angiopoietin-2 involves VEGF in human endothelial cells
5th International Symposium on the Biology of Endothelial Cells, Dresden, Abstracts: 53

Goettsch W, Gryczka C, Ellinghaus P, Morawietz H (2005)
Identification of marker genes of human arterial endothelial cells
5th International Symposium on the Biology of Endothelial Cells, Dresden, Abstracts: 51

Duerrschmidt N, Stielow C, Muller G, Morawietz H (2005)
NO-mediated downregulation of NAD(P)H oxidase by laminar shear stress in human endothelial cells
5th International Symposium on the Biology of Endothelial Cells, Dresden, Abstracts: 47

Catar RA, Niemann B, Rohrbach S, Muller G, Barton M, Morawietz H (2005)
Native and oxidized low-density lipoprotein activates the endothelin system in human endothelial cells
5th International Symposium on the Biology of Endothelial Cells, Dresden, Abstracts: 42

Stielow C, Muller G, Morawietz H (2005)
Role of Nox isoformes in NAD(P)H oxidase-mediated superoxide anion formation in endothelial cells
5th International Symposium on the Biology of Endothelial Cells, Dresden, Abstracts: 23

Gryczka C, Goettsch W, Morawietz H (2005)
Regulation of Angiopoietin-2 by shear stress involves VEGF
J. Vasc. Res., 42 (Suppl. 2): II/60

Duerrschmidt N, Stielow C, Muller G, Morawietz H (2005)
Regulation of Nox isoformes by shear stress in human endothelial cells
J. Vasc. Res., 42 (Suppl. 2): II/57

Muller G, Catar R, Niemann B, Barton M, Kneels L, Wendel M, Morawietz H (2005)
Upregulation of endothelin receptor B in human endothelial cells by low-density lipoproteins: role of protein kinase C
Ninth International Conference on Endothelin, Park City, UT, Book of Abstracts, P-006, 53

Hagen B, Roch B, Morawietz H, Müller G, Schröder H-E (2005)
Molekularbiologische Untersuchungen zum Pathomechanismus der Wirkung von Phospholipid-Antikörpern auf humane umbilikale venöse Endothelzellen
Z. Rheumatol. (2005), 64 (Suppl. 1):I/43

Stielow C, Muller G, Morawietz H (2005)
Expression of Nox isoformes in human endothelial cells
13. Atherosklerose-Symposium, Erfurt, Abstracts: PII-5

Catar R, Niemann B, Rohrbach S, Muller G, Barton M, Morawietz H (2005)
Native and oxidized low-density lipoprotein activates the endothelin system in human endothelial cells
13. Atherosklerose-Symposium, Erfurt, Abstracts: PI-4

Duerrschmidt N, Stielow C, Muller G, Morawietz H (2005)
Shear stress-dependent regulation of NAD(P)H oxidase in human endothelial cells
13. Atherosklerose-Symposium, Erfurt, Abstracts: 6

Ellinghaus P, Scheubel RJ, Dobrev D, Ravens U, Holtz J, Hütter J, Nielsch U, Morawietz H (2005)
Identifizierung von kammer-spezifischen Genen in humanem Atrium und Ventrikel
Z. Kardiol. (German J. Cardiol.), 94 (Suppl. 1):V1555

Goettsch W, Ellinghaus P, Gryczka C, Morawietz H (2005)
Die Notch-Zielgene Hey1 und Hey2 vermitteln einen arteriellen Phänotyp in humanen Endothelzellen
Z. Kardiol. (German J. Cardiol.), 94 (Suppl. 1):V253

Goettsch W, Gryczka C, Ellinghaus P, Morawietz H (2005)
Identification of marker genes of human arterial endothelial cells
Pflügers Arch. (Eur. J. Physiol.), 449:S58

Ellinghaus P, Scheubel RJ, Dobrev D, Ravens U, Holtz J, Huetter J, Nielsch U, Morawietz H (2005)
Comparing the global mRNA expression profile of human atrium and ventricle using high density oligonucleotide arrays
Pflügers Arch. (Eur. J. Physiol.), 449:S47

Niemann B, Rohrbach S, Catar R, Muller G, Barton M, Morawietz H (2005)
Native LDL upregulates endothelin-converting enzyme-1 in human endothelial cells
Clin. Hemorheol. Microcirc., 32:315

Duerrschmidt N, Stielow C, Muller G, Morawietz H (2005)
Regulation of NAD(P)H oxidase by shear stress in human endothelial cells
Clin. Hemorheol. Microcirc., 32:298-299

Publications 2004

Goettsch W, Augustin HG, Morawietz H (2004)
Down-regulation of endothelial ephrinB2 expression by laminar shear stress
Endothelium – J. Endoth. Cell Res., 11:259-265

Schubert A, Morawietz H (2004)
Application of biomechanical forces on endothelial cells
In: „Methods in endothelial cell biology“, Ed. by H. G. Augustin, Springer-Verlag, Berlin-Heidelberg-New York, 93-101

Abstracts 2004

Niemann B, Rohrbach S, Catar R, Muller G, Barton M, Morawietz H (2004)
Native LDL induces endothelin-converting enzyme-1 in primary human endothelial cells
Circulation, 110 (Suppl.):III-209-III-210

Wunder C, Eichelbronner O, Frantz S, Goettsch W, Morawietz H, Roewer N (2004)
Endothelin-1 hat keinen Einfluss auf die Regulation der hepatischen Mikrozirkulation im Ischämie/Reperfusion-induzierten frühen SIRS
Anasth. Intensivmed., 45:697-698

Niemann B, Rohrbach S, Catar R, Muller G, Barton M, Morawietz H (2004)
Native LDL upregulates endothelin-converting enzyme-1 in human endothelial cells
J. Vasc. Res., 41: 0351 458-

Duerrschmidt N, Stielow C, Muller G, Morawietz H (2004)
NO-mediated downregulation of NAD(P)H oxidase by laminar shear stress in human endothelial cells
J. Vasc. Res., 41:448

Goettsch W, Augustin HG, Morawietz H (2004)
Regulation of ephrin-B2 and angiopoietin-2 by laminar shear stress in human endothelial cells
International Society of Nephrology (ISN) Forefront Conference, Dresden, Abstracts: 15

Duerrschmidt N, Stielow C, Muller G, Morawietz H (2004)
Downregulation of NAD(P)H oxidase by laminar shear stress in human endothelial cells
International Society of Nephrology (ISN) Forefront Conference, Dresden, Abstracts: 4

Scheubel RJ, Zorn H, Silber RE, Kuss O, Morawietz H, Holtz J, Simm A (2004)
Age-dependent depression in circulating endothelial progenitor cells in patients under coronary artery bypass grafting
Eur. Heart J., 25 (Suppl.):263

Rohrbach S, Ruhs S, Müller-Werdan U, Holtz J, Morawietz H (2004)
Katecholamine induzieren Superoxidanionbildung und NAD(P)H-Oxidase-Untereinheiten-Expression in Kardiomyozyten
Z. Kardiol. (German J. Cardiol.), 93 (Suppl. 3):III/4

Morawietz H, Rohrbach S, Ruhs S, Müller-Werdan U, Holtz J (2004)
Catecholamines induce superoxide anion formation and NAD(P)H oxidase subunit expression in cardiomyocytes
Pflügers Arch. (Eur. J. Physiol.), 447:S24

Morawietz H, Duerrschmidt N, Zerkowski HR (2004)
Downregulation of NAD(P)H oxidase subunit protein expression by ACE inhibitor therapy in failing human myocardium
Pflügers Arch. (Eur. J. Physiol.), 447:S100

Publications 2003

Scheubel RJ, Zorn H, Silber RE, Kuss O, Morawietz H, Holtz J, Simm A (2003)
Age-dependent depression in circulating endothelial progenitor cells in patients undergoing coronary artery bypass grafting
J. Am. Coll. Cardiol., 42:2073-2080