Information for Pediatricians

• B-cell disorders/variable immunodeficiencies/agammaglobulinemias
• T-cell disorders
• Combined immunodeficiencies
• Neutropenias and granulocyte function disorders (septic granulomatosis)
• Periodic fever syndromes
• Other congenital immunodeficiencies
• Stem cell transplantation, including follow-up

• Unusual susceptibility to infections (in early childhood, >12 infections/year without hospital stays may still be within the normal range)
• Particularly severe infections (with hospital stays)
• Infections by unusual pathogens
• Chronic diarrhea and failure to thrive/growth disorders
• Swollen lymph nodes or spleen
• Unclear, recurrent fever
• Repeated deep abscesses of the skin and/or other organs
• Fungal infections of the oral mucosa or other skin areas beyond the first year of life
• Congenital immunodeficiencies or suspicious symptoms in other family members
• Complications from live vaccinations (rotavirus, polio, tuberculosis, measles, chickenpox)
• Clustering of autoimmune phenomena

• Recurrent fever episodes without an identifiable focus
• Prolonged fever without an identifiable focus

At the University Center for Chronic Immunodeficiencies, we provide diagnosis, consultation, and therapy for patients with a confirmed diagnosis of immunodeficiency or autoinflammatory disease, or those suspected of having such conditions.

Some immune disorders become apparent or are diagnosed later in life or in adulthood. If your patient already has a diagnosed immunodeficiency, or if you strongly suspect a congenital or acquired immunodeficiency, a consultation for adult patients at the University Center for Chronic Immunodeficiencies is possible.

For this, we request an initial blood draw (differential blood count, creatinine/GFR, gamma-glutamyl transferase, ALT, immunoglobulins A, G, M, E, and possibly vaccine titers), ideally not older than 3 months.

Additionally, please send us the completed questionnaire, a letter of referral indicating suspicion of immunodeficiency for the Immunology department, and the summarized immunodeficiency-related previous findings/medical reports.

Based on this information, a decision will be made on whether consultation and further diagnostics are advisable, and we will provide you with an appointment. You will be informed of this appointment in writing.